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The Best pet urine enzyme cleaner of 2022 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best pet urine enzyme cleaner of 2022. Check our ranking below.

2,474 Reviews Scanned

Rank No. #1
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
  • Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
  • Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
  • Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
  • Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
  • Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
Rank No. #2
Nature’s Miracle Urine Destroyer Plus Dog, 32 Ounces, Enzymatic Formula, Ready-to-Use
  • FOR DOG URINE MESSES: Begins to break down and remove stains immediately on contact.
  • POWERFUL FORMULA: Just soak the affected area, allow to work for 15 minutes, then blot up stain with a clean cloth.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
  • SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets and in your home.
Rank No. #3
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
  • THE POWER OF ONE: This versatile product is the only probiotic cleaner you need, providing powerful cleaning performance in a wide variety of applications. Multipurpose use: Maintain clean drain lines and septic tanks to prevent clogs and potential buildup. Clean and deodorize trash bins, stains and odors on floors, carpets, bathroom surfaces, kitchen surfaces, and more.
  • ACTIVE UP TO 21 DAYS: Our specialized probiotics continue to clean soils in cracks, grout and tough to reach places. Simply spray & let the probiotics do the dirty work!
  • NATURALLY, SUPERIOR RESULTS: A special blend of enzyme-producing probiotics break down complex proteins, fats, oils, greases, and other organic waste. The enzymes digest the soils until they have been eliminated, providing a long-lasting, continuous clean without leaving a residue or harmful by-products behind.
  • ELIMINATE ODOR: Provide total odor control by eliminating the actual source of even the most pungent organic malodors naturally, including rotting food, urine, feces, vomit, and trash. Plus, the fresh lemon and sage fragrance leaves behind a light, pleasant scent that rejuvenates the air of any environment.
  • MADE IN THE USA - 1 Gallon Bottle
Rank No. #4
Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz
  • DESTOYS URINE ODORS THE FIRST TIME: Urine elimination technology neutralizes and removes odors on contact for immediate freshness
  • REMOVES PET STAINS AND MORE: Effectively tackles pet stains, food stains, and other tough messes
  • HELPS PREVENT REMARKING: Discourages pets from returning to make a mess in the same spot
  • SUITABLE FOR USE AROUND PETS: Suitable for use around pets when used as directed
  • MULTIPURPOSE USE: Effective on most carpets, fabrics and hard surfaces for versatile cleaning
SaleRank No. #5
Nature’s Miracle Advanced Stain and Odor Eliminator Dog, 32 Ounces, Fresh Scent, Severe Mess Enzymatic Formula For Tough Pet Messes
  • FOR SEVERE DOG MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from dog urine, diarrhea, vomit and other bio-based accidents.
  • LIGHT FRESH SCENT: Dog odor control formula gets your home smelling clean again.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • DISCOURAGES RESOILING: Removes the odor from even the toughest dog messes.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
Rank No. #6
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz
  • PET STAIN AND ODOR REMOVER: Things can get a little messy when your pet is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest smells & dirtiest spots left behind by your beloved pets.
  • EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula three times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors.
  • FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; It is a pet-safe and family-friendly cleaning option
  • MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, & other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and stream features so you can pick the best way to clean up
  • SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy.
SaleRank No. #7
Kinzua Environmental Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon
  • Powerful & Effective Cleaner: Each gallon of Urine B-Gone is loaded with 200 billion microbe colonies, working tirelessly to liquefy, digest, and eliminate urine and poop; This high-strength formula ensures your home stays fresh and free from unpleasant odors
  • Deep Penetration, Lasting Results: Urine B-Gone doesn’t just mask odors; it attacks them at the source; This powerful enzyme cleaner penetrates deep into any carpet and upholstery, removing stains and neutralizing smells even from padding and the floor beneath; Its versatile formula makes it suitable for all cleaning tasks, ensuring every surface is left fresh and spotless
  • Safe for Your Home: Our natural enzyme formula is safe to use around pets and children when used as directed; It’s designed to be gentle yet highly effective, providing peace of mind while maintaining a clean and odor-free environment; Enjoy the fresh scent of our urine cleaner
  • Versatile Cleaning Solution: Beyond pet stains, Urine B-Gone is ideal for a variety of applications; Use it in your laundry to pre-spray soiled areas or even in drains, urinals, and toilets; This all-in-one cleaner & odor remover makes tackling tough stains and odors simple and efficient
  • About Us: At Kinzua Environmental, we specialize in premium cleaning solutions that are safe and professional strength for both commercial and household applications
SaleRank No. #8
Nature’s Miracle Stain and Odor Remover Dog, Odor Control Formula, 32 oz
  • SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
  • LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
  • SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
SaleRank No. #9
Nature’s Miracle Stain And Odor Remover Dog 1.33 Gallons, Odor Control Formula, AccuShot Sprayer Refill 170 fl oz, Tough on Dog Urine, Feces, Vomit, Drool and Other Organic Stains and Odors
  • TOUGH ON STAINS AND ODORS: This stain and odor remover is tough on dog urine, feces, vomit, drool and other organic stains and odors.
  • MULTI-SURFACE USE: When used and stored as directed, this product is safe for use on carpets, hard floors, furniture, fabrics and more.
  • SAFE FOR PETS AND HOME: We’ve been loved by pet parents for over 35 years, so we know the importance of having an effective stain and odor remover that, when used and stored as directed, is safe to use around pets.
  • CITRUS SCENT: In addition to removing stains and odors, this product freshens with a light citrus scent.
Rank No. #10
Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic
  • STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
  • PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
  • BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
  • PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
  • MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts

Last update on 2025-06-05 / Affiliate links / Images from Amazon Product Advertising API

How Do You Buy The Best pet urine enzyme cleaner?

Do you get stressed out thinking about shopping for a great pet urine enzyme cleaner? Do doubts keep creeping into your mind? We understand, because we’ve already gone through the whole process of researching pet urine enzyme cleaner, which is why we have assembled a comprehensive list of the greatest pet urine enzyme cleaner available in the current market. We’ve also come up with a list of questions that you probably have yourself.

We’ve done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for pet urine enzyme cleaner that you consider buying. Your questions might include the following:

  • Is it worth buying an pet urine enzyme cleaner?
  • What benefits are there with buying an pet urine enzyme cleaner?
  • What factors deserve consideration when shopping for an effective pet urine enzyme cleaner?
  • Why is it crucial to invest in any pet urine enzyme cleaner, much less the best one?
  • Which pet urine enzyme cleaner are good in the current market?
  • Where can you find information like this about pet urine enzyme cleaner?

We’re convinced that you likely have far more questions than just these regarding pet urine enzyme cleaner, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for pet urine enzyme cleaner, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible pet urine enzyme cleaner. Make sure that you are only using trustworthy and credible websites and sources.

We provide an pet urine enzyme cleaner buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information. How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available pet urine enzyme cleaner currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of pet urine enzyme cleaner has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an pet urine enzyme cleaner?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your pet urine enzyme cleaner.
  5. Customer Ratings: Number ratings grade pet urine enzyme cleaner objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their pet urine enzyme cleaner.
  7. Product Quality: You don’t always get what you pay for with an pet urine enzyme cleaner, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an pet urine enzyme cleaner is should be an indication of how long it will work out for you.

We always remember that maintaining pet urine enzyme cleaner information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding pet urine enzyme cleaner is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly! We’re here for you all the time. Contact us here. Or You can read more about us to see our vision.

FAQ:

Q: What are the best pet enzyme removers?

A: Nature’s Miracle Dog Enzymatic Stain&Odor Remover. Consider a 1-gallon bottle if you’re house training a puppy. … BUBBAS Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator. This enzyme cleaner works as a pre-wash stain treatment. … Rocco&Roxie Supply Co. … PetSafe Pet Loo Wee Care Enzyme Cleaner,16-oz. …

Q: What is the best cleaner for dog urine?

A: White Vinegar is a good and effective natural dog urine cleaner. After finishing Steps 1 and 2 described above, soak the area completely with undiluted white vinegar. Let it soak in well and sit for several minutes before blotting the area dry.

Q: What is the best pet stain and odor remover?

A: Accidents happen to the best of us, and our pets are no exception. Unfortunately, pet accidents can leave troubling stains and odors behind. A mix of vinegar, water, and baking soda can do wonders for pet stains, but when you need something heavy duty, you’ll want a quality pet stain and odor remover on your side.

Q: What is a good enzyme based cleaner?

A: The 10 Best Enzyme Drain Cleaners Green Gobbler Refresh. The formula inside each bottle of Green Gobbler Refresh (appx. … Black Diamond Stoneworks Get Serious. For large-scale commercial applications, there’s the 5-gallon bucket of Black Diamond Stoneworks Get Serious (around $100). Bio-Clean Ultimate Kit. … Helix Laboratories DrainScrub. … Roebic Septic Tank Treatment. … FDC Break Down. … More items…

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