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The Best pill to kill fleas of 2022 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best pill to kill fleas of 2022. Check our ranking below.

2,500 Reviews Scanned

Rank No. #1
PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs 2-25 lbs, 6 Doses
  • Powerful Ingredients: CAPACTION flea tablets contain the same active ingredients as CAPSTAR (nitenpyram)
  • Quick and Easy: This flea and tick pill kills fleas fast: begins working within 30 minutes
  • Proven Results: CAPACTION achieves greater than 90% effectiveness against adult fleas on dogs within 4 hours
  • Easy-to-Use: CAPACTION is provided in a convenient oral tablet. No prescription needed
  • Intended Use: CAPACTION oral flea tablets are intended for use on dogs weighing 2 to 25 pounds
Rank No. #2
CAPSTAR Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Medium & Large Dogs (Over 25 lbs), 6 Doses
  • Fast-Acting Flea Treatment: Capstar (nitenpyram) starts eliminating adult fleas in just 30 minutes
  • Tackle Flea Infestations Fast: With one dose of CAPSTAR, you can watch the dead fleas fall off your pet
  • Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose as often as once a day
  • No Prescription Needed: Fast, effective flea treatment that's available over the counter
  • Intended Use: Capstar Oral Flea Treatment for Large Dogs (57 mg) is safe for dogs and puppies 4 weeks and older that weigh 25.1-125 pounds
Rank No. #3
PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses
  • FAST-ACTING: One oral flea tablet starts killing fleas within 30 minutes of administration.
  • SAFE TO USE: This oral flea medication is safe for kittens and cats from 2-25 lbs. 4 weeks and older, when used as directed.
  • TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas simply apply another dose as often as once a day. CapAction Flea Pills are even safe for use on pregnant or breeding cats.
  • EASY TO USE: Without the mess and rubbing off of a flea and tick topical treatment and without the need of a veterinarian prescription this cat flea tablet is administered orally to kill adult fleas fast.
  • KILL FLEAS EFFICIENTLY: CapAction flea treatment has 6 doses and kills adult fleas that may cause allergy dermatitis.
Rank No. #4
Advantus Dog Fast Acting Oral Flea Treatment Soft Chews Dogs 23 - 110 lbs. | 7 ct.
  • Advantus (imidacloprid) is a flavored soft chew that, with one dose, starts killing adult fleas within one hour so your dog can get back to enjoying life
  • This chewable flea treatment is available without a prescription
  • Treats flea infestations on dogs and puppies 10 weeks of age and older and weighing from 23 - 110 lbs.
  • Easy-to-give soft chew that can be administered to your dog as often as once daily if they become re-infested
  • Advantus is also available for dogs ranging in weight between 4 and 22 lbs.
SaleRank No. #5
CAPSTAR (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses
  • CAPSTAR (nitenpyram) starts killing adult fleas in just 30 minutes
  • With one dose of CAPSTAR, you can watch the dead fleas fall off your pet
  • If your pet gets reinfested with fleas, simply give another dose as often as once a day
  • CAPSTAR is a fast, effective cat flea treatment that is available over the counter
  • CAPSTAR Oral Flea Treatment for Cats (11.4 mg) is safe for cats and kittens 4 weeks and older that weigh 2-25 pounds
Rank No. #6
Advantus Dog Fast Acting Oral Flea Treatment Soft Chews Dogs 4 - 22 lbs. | 7 ct.
  • Advantus (imidacloprid) is a flavored soft chew that, with one dose, starts killing adult fleas within one hour so your dog can get back to enjoying life
  • This chewable flea treatment is available without a prescription
  • Treats flea infestations on dogs and puppies 10 weeks of age and older and weighing from 4 - 22 lbs.
  • Easy-to-give soft chew that can be administered to your dog as often as once daily if they become re-infested
  • Advantus is also available for large dogs ranging in weight between 23 and 110 lbs.
Rank No. #7
Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes
  • NATURAL FLEA AND TICK PREVENTION FOR DOGS: Our dog flea treatment chews are made with natural ingredients and offer a gentle way to prevent fleas and ticks from the inside out, keeping your dog comfortable and protected. This expert-recommended formula provides gentle flea treatment for both dogs and puppies. Each can contains 200 chews, offering over 3 months of use
  • DAILY PROTECTION, LONG-TERM DEFENSE: Woyamay dog flea and tick treatment treats provide daily protection and help reduce the impact of fleas, ticks, mosquitoes, and so on. They help your dog develop a natural defense against fleas and ticks from within and are suitable for small, medium, and large dogs. An easy and pet-friendly alternative to flea drops, sprays, and shampoos
  • EFFECTIVE HEALTH SUPPORT: Our flea treatment dogs soft chews provide natural health support for dogs of all ages and breeds. Each soft chew is enriched with coconut oil, flaxseed, and brewer's yeast, and contains no harsh chemicals or artificial additives. Gentle for both puppies and senior dogs, these chews offer a gentle yet effective flea prevention solution
  • SKIN & COAT CARE: Our chewable for dogs is formulated with skin-nourishing ingredients, including fish oil and B vitamins. These chews moisturize and protect your dog's skin while promoting a shiny, healthy coat. With consistent use, they improve coat appearance and support effective prevention of fleas and ticks
  • DELICIOUS & EASY TO USE: These flea and tick chewables for dogs feature a delicious chicken flavor that even picky eaters will love. They are easy to administer—simply offer them as a snack or crush and mix them into a meal for effortless serving. Our tasty chicken-flavored chewables make flea treatment for dogs a snack, not a chore
SaleRank No. #8
Flea and Tick Prevention for Dogs Chewables -Made in USA- Natural Dog Flea and Tick Treatment - Oral Flea Pills - Vet Recommended Flea and Tick Chews - All Breeds & Sizes - 120 Soft Treats (Chicken)
  • Flea And Tick Prevention For Dogs: Natural essentials your dog needs in a perfectly balanced formula to boost skin, coat & immune health and prevent fleas & ticks from laying eggs on your dog’s coat.
  • Dog Flea And Tick Treatment with Skin & Coat Support : Flax seed + Neem + Coriander for dogs naturally repels flea & tick when used daily. Vet Treat Flea and Tick chews provide additional benefits to your dog's skin & coat health with Vitamin B Blend.
  • No Garlic, No Chemicals: All natural and science-backed ingredients. Natural alternative to synthetic pesticides. Dog skin & coat supplement for flea and tick prevention.
  • Vet Recommended + Made In U.S.A + Clinically Tested: Made in the U.S.A in an FDA-registered facility by veterinarians and animal nutritionists. Clinically tested for safety by a third-party laboratory in the US.
  • Flea & Tick Control For All: Tasty chicken-flavored dog flea and tick repellent chews are safe and effective for all ages, sizes & breeds. We left no dog behind.
SaleRank No. #9
Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
  • Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
  • Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
  • Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
  • Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
Rank No. #10
Flea Away All Natural Supplement for Fleas, Ticks, and Mosquitos Prevention for Dogs and Cats, 100 Chewable Treat Tablets, Single
  • NATURAL FLEA & TICK CONTROL: Flea Away is an all natural vitamin complex, made to FDA human standards and specifically formulated for dogs and cats, creating a safe barrier from fleas, ticks and mosquitos.
  • NO PESTICIDES: Flea Away repels fleas, ticks, & mosquitoes naturally, with no toxic chemicals or residue. Safe for both nursing mother and her litter.
  • ADDITIONAL BENEFITS: our Vitamin complex promotes healthier skin, reduces shedding, shinier coat, better joints and is Liver flavored. Your pet will love them!
  • NO MORE BITES: The difference from alternate flea repellents is with Flea Away, fleas are naturally diverted from your pet before biting your pet. Helps dogs and cats with allergic reaction to flea bites.
  • DOSAGE: When given every day, it will take less than 30 days for your pet to build up The appropriate level to fight off pests. Sourced and manufactured in the USA for year round use

Last update on 2025-07-10 / Affiliate links / Images from Amazon Product Advertising API

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