18 Best Opc Supplement of 2025 – Romance University
After hours researching and comparing all models on the market, Romance University finds out Top 18 Best Opc Supplement of 2025. Check our ranking below.
2,981 Reviews Scanned
Rank No. #1
Terry Naturally Clinical OPC Extra Strength - Cardiovascular Health & Focus Support - Supplement with Grape Seed Extract - Immune Support Supplement - 60 Softgels
- Immune & Heart Supplement: This dietary supplement is formulated to support cell health, heart health, and immune health; Clinical OPC also aids focus and concentration
- Cardiovascular Supplement with French Grape Seed Extract: This supplement is backed by 6 scientific studies; no artificial colorings, flavorings, or preservatives
- Daily Immune Support Supplement: For immune and cell support, take 1 softgel daily; may take up to 3 times a day for enhanced benefits; if pregnant or nursing, consult a h healthcare practitioner before use
- Allergen-Friendly Dietary Supplement: This heart supplement contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives
- Your Health & Our Passion: Our supplements combine the best of science and nature, formulated to support your health and inspire you to make lasting changes to your health
Rank No. #2
Terry Naturally Clinical OPC - Cardiovascular Health & Focus Support Supplement - Dietary Supplement with Grape Seed Extract & Sunflower Lecithin - Immune Support Supplement - 150 mg, 60 Softgels
- Immune & Heart Supplement: This dietary supplement is formulated to support cell health, heart health, and immune health; Clinical OPC also aids focus and concentration
- Cardiovascular Supplement with Sunflower Lecithin: Contains sunflower lecithin, which supports the dietary supplement's absorption without the use of artificial additives
- Daily Immune Support Supplement: For immune and cell support, take 1 softgel daily; may take up to 3 times a day for enhanced benefits, or as recommended by your healthcare practitioner
- Allergen-Friendly Dietary Supplement: This heart supplement contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives
- Your Health & Our Passion: Our supplements combine the best of science and nature, formulated to support your health and inspire you to make lasting changes to your health
Rank No. #3
OPC-3 Isotonix - Antioxidant Supplement - Pycnogenol, Grape Seed Extracts, Bilberry, Red Wine & Pine Bark Extracts - for Heart & Circulatory Support - Isotonic, Vegan, Gluten Free - 90 Servings
- Powerful Antioxidant Supplement – Features Pycnogenol, grape seed extract, pine bark extract, red wine extract, bilberry, and citrus bioflavonoids for comprehensive antioxidant support.
- Supports Healthy Circulation & Cardiovascular Wellness – Helps maintain healthy blood flow and promotes normal blood vessel dilation, contributing to overall heart health.
- Helps Maintain Healthy Cholesterol Levels – Grape seed extract assists in maintaining healthy cholesterol for balanced cardiovascular support.
- Promotes Energy & Vitality – Formulated to support healthy oxygen delivery to muscles and vital organs for daily energy and performance.
- Provides 95% Nutrient Absorption – Isotonic delivery system ensures rapid and efficient absorption of key nutrients for maximum effect.
Rank No. #4
Zazzee High Strength Grape Seed 50:1 Extract, 180 Vegan Capsules, 95% Polyphenols, 400 mg per Capsule, 6 Month Supply, Standardized and Concentrated 50X Extract, Non-GMO, Made in The USA
- OUTSTANDING VALUE: Our Extra Strength Grape Seed Extract contains 20,000 mg strength per capsule, is standardized to 95% Polyphenols, AND contains 180 capsules per bottle – an amazing value! A single bottle contains a 6 month supply. Compare this to other leading brands that require 2 capsules per serving, contain less than 180 capsules, and use a much less potent, non-extract powder. Our Extra Strength Grape Seed Extract is a bargain not be found elsewhere!
- 95% POLYPHENOLS: Polyphenols are the “good stuff”, the beneficial compound in Grape Seed Extract that provides the desired results. Our Grape Seed Extract has been standardized to contain a minimum of 95% Polyphenols, which is one of the highest standardization numbers available. The higher the numbers, the more potent the extract. Clearly, not all Grape Seed Extracts are created equal!
- POTENT 50:1 EXTRACT / 20,000 MG STRENGTH PER CAPSULE / HIGH BIOAVAILABILITY: Each capsule contains 20,000 mg strength of Grape Seed Extract from a potent, powerful 50:1 extract. Combine that with a minimum of 95% Polyphenols, and our Extra Strength Grape Seed Extract is one of the strongest dosages available! The key to our extraction is an all-natural process that ensures high bioavailablity - which means your body receives maximum absorption and maximum benefits.
- NATURAL, VEGAN & NON-GMO: All ingredients, including the capsule, are 100% vegan. Our Extra Strength Grape Seed Extract does not contain any sweeteners, artificial flavors, wheat, corn, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Enjoy the amazing benefits of our potent Grape Seed Extract without worrying about what else might be hiding in each capsule!
- GOLD STANDARD PRODUCTION: Your health and safety mean everything to us. For that reason, our Extra Strength Grape Seed Extract is manufactured in the USA, in a fully certified facility with adherence to good manufacturing policies and under the most stringent quality control. You can rest assured that you get the best value for your money!
Rank No. #5
Standard Process OPC Synergy - Supports Antioxidant Activity - Aids Cellular Function & Brain Health - Aids a Healthy Heart - Supplement for Eye Health - 150 Tablets
- Antioxidant Support with OPC Synergy: Provides a synergistic blend that exhibits antioxidant activity and supports cell functioning*
- Antioxidant-Dense Ingredients: This supplement provides ingredients with antioxidant activity*; OPC Synergy maintains capillary integrity and supports normal cell function*
- Aids Eye & Brain Health: This synergy supplement helps maintain normal brain health and function; this eyesight supports aids eye health*
- Whole Food-Based Brain Support: Supports the complex processes associated with aging*; supports a healthy cardiovascular system*
- About Standard Process: Standard Process has been an industry leader in whole food-based nutritional supplements for over 95 years
Rank No. #6
All Nature Super OPC Plus (Grape Seed, Red Wine and Pine Bark Extract)
- 100 capsules, 450 mg of Super OPC per capsule
- 250mg of grape seed extract per capsule
- 100mg of Red Wine extract per capsule
- 100mg of Pine Bark extract per capsule
- Serving size is 2 capsules or 900mg total
Rank No. #7
OPC-3 Isotonix - Antioxidant Supplement - Pycnogenol, Grape Seed Extracts, Bilberry, Red Wine & Pine Bark Extracts - for Heart & Circulatory Support - Isotonic, Vegan, Gluten Free - 30 Servings
- Powerful Antioxidant Supplement – Features Pycnogenol, grape seed extract, pine bark extract, red wine extract, bilberry, and citrus bioflavonoids for comprehensive antioxidant support.
- Supports Healthy Circulation & Cardiovascular Wellness – Helps maintain healthy blood flow and promotes normal blood vessel dilation, contributing to overall heart health.
- Helps Maintain Healthy Cholesterol Levels – Grape seed extract assists in maintaining healthy cholesterol for balanced cardiovascular support.
- Promotes Energy & Vitality – Formulated to support healthy oxygen delivery to muscles and vital organs for daily energy and performance.
- Provides 95% Nutrient Absorption – Isotonic delivery system ensures rapid and efficient absorption of key nutrients for maximum effect.
Rank No. #8
Carlyle Grape Seed Extract 24,000 mg Equivalent 240 Capsules | Maximum Strength Standardized Extract | Non-GMO, Gluten Free
- GRAPE SEED EXTRACT: Get powerful support with Grapeseed quick-release capsules!
- POTENT FORM: Equivalent of 24,000 mg Grape Seed powder per serving
- ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
- CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
- NATURALLY FREE OF: Gluten, Wheat, Artificial Flavor, Artificial Sweetener, Preservatives & Non-GMO
Rank No. #9
Terry Naturally Clinical OPC Extra Strength - Healthy Heart & Artery Support - Aids Brain Health & Function for Focus and Concentration - Offers Antioxidant Activity - 400 mg, 90 Softgels
- Liver Support with Antioxidant Activity: Oligomeric proanthocyanidins (OPCs) are the powerful, health-supporting nutrients in grape seed extract, a botanical extract that offers a diverse array of health benefits*
- Heart Health & Artery Support: This herbal supplement offers cellular health support while aiding healthy blood circulation in your heart and arteries
- Brain Health Support: This cellular supplement also offers brain health support for focus and concentration*
- Recommended Dosage: For best results, take 1 antioxidant support softgel daily; you may take up to three times a day for further benefits
- Your Health & Our Passion: Our supplements combine the best of science and nature, formulated to support your health and inspire you to make lasting changes to your health
Rank No. #10
Organic Grape Seed Capsules – 520mg, 100 Count – Polyphenols & OPC Antioxidants
- PREMIUM ORGANIC GRAPE SEED CAPSULES – Each serving provides 520mg of pure, organic grape seed powder, offering a clean and natural supplement made without fillers, additives, or preservatives.
- NATURAL SOURCE OF POLYPHENOLS & OPCs – Grape seed is rich in plant-based antioxidants, including polyphenols and oligomeric proanthocyanidins (OPCs), which help protect the body against everyday stressors.
- SUPPORTS CIRCULATION & PERFORMANCE – Commonly used for promoting healthy circulation and endurance, grape seed can be a natural addition to active lifestyles and daily routines.
- CLEAN, VEGAN & NON-GMO FORMULA – Made with certified organic grape seed and plant-based capsules. Free from gluten, soy, dairy, microcrystalline cellulose, magnesium stearate, and silicon dioxide.
- HIGH QUALITY & TRUSTED SUPPLEMENT – Crafted with care and tested for purity, these capsules deliver an organic and straightforward option for those seeking the natural benefits of grape seed.
Rank No. #11
NOW Foods Supplements, Pine Bark Extract 240 mg, 90% OPC Pine Bark Extract, (from the Inner Bark of Chinese Red Pine), 90 Veg Capsules
- 90% OPC PINE PARK EXTRACT: Derived from the inner bark of Chinese red pine and prized for its powerful free radical-scavenging elements
- COMPLEMENTARY INGREDIENT: Green tea extract with EGCg included for its abundant flavonols that complement the oxidant neutralizing of pine bark extract
- CERTIFICATIONS/CLASSIFICATIONS: Dairy Free, Egg Free, Made without Gluten, Nut Free, Soy Free, Vegan
- Vegetarian/Vegan
- Kosher
Rank No. #12
THORNE - Grape Seed Extract (Formerly O.P.C.-100) - Grape Seed Phytosome for Antioxidant Support* - 60 Capsules
- Grapeseed Extract: OPCs are important health-promoting flavonoids from grape seed*
- Optimal Aborption: OPCs bound to phospholipids for optimal absorption
- Blood Vessels: Strengthens blood vessels to decrease bruising*
- Antioxidant: Contains important antioxidant flavonoids*
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
Rank No. #13
Now Supplements, Grape Seed Extract, Maximum Strength 500 mg (a Highly Concentrated Extract with a Minimum of 90% Polyphenols), 90 Veg Capsules
- MINIMUM OF 90 PERCENT POLYPHENOLS: Over four times the grape seed extract as in our regular strength product (60 mg per capsule), offering even more free radical protection*
- HIGHLY CONCENTRATED EXTRACT: Grape seed OPCs may help to support the health of vascular, bone, kidney, brain, and other tissues by supporting a healthy, balanced immune response to oxidative and metabolic stress*
- CLASSIFICATIONS/CERTIFICATIONS: Non-GMO, Quality GMP Assured, Kosher, Vegan/Vegetarian, Soy Free, Dairy Free, Egg Free, Nut Free, Made Without Gluten
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
- Packaged in the USA by a family owned and operated company since 1968
Rank No. #14
FrenchGlory OPC90: Isotonic OPC Antioxidant 3 Month Supplement
- Made of the best OPC 3 ingredients in the world, imported from France;
- Finest OPC oligomers for efficient absorption, free of high molecular weight polymer;
- OPC used in this product was invented in France by French scientist Jacques Masquelier - 3 OPC materials of the highest quality, made by a native French company called DRT Nutraceutics;
- All natural; Sweet and sour, like grape juice, but slightly bitter background taste.
SaleRank No. #15
NOW Supplements, Grape Seed 100 mg - Standardized Extract, Highly Concentrated Extract with a Minimum of 90% Polyphenols, with Vitamin C, 100 Veg Capsules
- Grape Seed Extract is a highly concentrated extract with a minimum of 90% polyphenols, including oligomeric proanthocyanidins (OPCs), which are the potent water-soluble free radical scavenging compounds found in grape seeds*
- A growing body of research indicates that grape seed OPCs may help to support the health of vascular, bone, kidney, brain and other tissues by supporting a healthy immune response to normal oxidative and metabolic stress*
- Vitamin C has been added for its antioxidant power*
- Take 1 capsule twice daily with food
- Packaged in the USA by a family owned and operated company since 1968.
Rank No. #16
Isotonix OPC-3 Antioxidant Chews | Circulation, Vision & Skin Support | Grape Seed, Red Wine, Pine Bark (Pycnogenol®), Bilberry & Citrus Bioflavonoids | Chewable Antioxidant Supplement - 30 Count
- BROAD-SPECTRUM ANTIOXIDANT SUPPLEMENT – Featuring grape seed, red wine, pine bark (Pycnogenol), bilberry, and citrus bioflavonoids to help protect against oxidative stress and support overall wellness.
- SUPPORTS CIRCULATION & VASCULAR HEALTH – Plant-based flavonoids such as OPCs (oligomeric proanthocyanidins) are known to promote healthy blood flow and vascular function.
- EYE & VISION SUPPORT – Bilberry extract is naturally rich in anthocyanins, antioxidants studied for their role in supporting healthy vision and eye comfort.
- SKIN & CELLULAR HEALTH – Antioxidants from pine bark extract (Pycnogenol) and grape seed help defend against free radicals that impact skin and cellular health.
- DELICIOUS & CONVENIENT – Chewable soft chews with natural flavors make it easy to enjoy daily antioxidant support anytime, anywhere.
Rank No. #17
EuroMedica Clinical OPC - Cardiovascular Health & Focus Support Supplement - Dietary Supplement with Grape Seed Extract & Sunflower Lecithin - Immune Support Supplement Formula - 60 Softgels
- Immune & Heart Supplement: This dietary supplement is formulated to support cell health, heart health, and immune health; Clinical OPC also aids focus and concentration
- Cardiovascular Supplement with Sunflower Lecithin: Contains sunflower lecithin, which supports the dietary supplement's absorption without the use of artificial additives
- Daily Immune Support Supplement: For immune and cell support, take 1 softgel daily; may take up to 3 times a day for enhanced benefits, or as recommended by your healthcare practitioner
- Allergen-Friendly Dietary Supplement: This heart supplement contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives
- Optimal Health Support with EuroMedica: Our supplement formulas are inspired by our respect for traditional health approaches and a desire to continually advance health science
Rank No. #18
LABO Nutrition Vitale OPCs | Premium European Grape Seed Extract with Aronia, Citrus Bioflavonoids | Supports Circulation, Skin Health and Cellular Protection | 100% polyphenols 90 Softgels
- Premium Grape Seed Extract with Enhanced Potency – Features European VP-100 Grape Seed Extract, delivering 100% polyphenols with ≥99% proanthocyanidins, offering up to 2.3 times the potency of French Maritime Pine Bark Extract. Aronia (Chokeberry) Extract standardized to 25% anthocyanidins and Citrus Bioflavonoids containing 50% hesperidin add powerful antioxidant support.
- Includes BioPerine Black Pepper Extract to optimize nutrient absorption and Cap-e tested for antioxidant capacity. Vitale OPCs can penetrate living cells to protect them from the inside out, enhancing overall cellular protection.
- OMaxFresh Technology for Freshness and Potency – Softgels are made with OmaxFresh technology to maintain maximum freshness and potency throughout their shelf life. Free from gluten, wheat, dairy, preservatives, and artificial coloring, the formula supports a healthy inflammatory response and immunity
- One softgel daily provides a 90-day supply of powerful antioxidant defense, as per its ORAC value. This potent blend helps support circulation, blood vessel health, keeping skin and body vibrant and healthy.
- Supports skin hydration, elasticity, and overall skin health with antioxidant protection.
How Do You Buy The Best Opc Supplement?
Do you get stressed out thinking about shopping for a great Opc Supplement? Do doubts keep creeping into your mind? We understand, because we’ve already gone through the whole process of researching Opc Supplement, which is why we have assembled a comprehensive list of the greatest Opc Supplement available in the current market. We’ve also come up with a list of questions that you probably have yourself.
Romance University has done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for Opc Supplement that you consider buying. Your questions might include the following:
- Is it worth buying an Opc Supplement?
- What benefits are there with buying an Opc Supplement?
- What factors deserve consideration when shopping for an effective Opc Supplement?
- Why is it crucial to invest in any Opc Supplement, much less the best one?
- Which Opc Supplement are good in the current market?
- Where can you find information like this about Opc Supplement?
We’re convinced that you likely have far more questions than just these regarding Opc Supplement, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.
Potential sources can include buying guides for Opc Supplement, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible Opc Supplement. Make sure that you are only using trustworthy and credible websites and sources.
Romance University provides an Opc Supplement buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information. How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available Opc Supplement currently available on the market.
This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:
- Brand Value: Every brand of Opc Supplement has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
- Features: What bells and whistles matter for an Opc Supplement?
- Specifications: How powerful they are can be measured.
- Product Value: This simply is how much bang for the buck you get from your Opc Supplement.
- Customer Ratings: Number ratings grade Opc Supplement objectively.
- Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their Opc Supplement.
- Product Quality: You don’t always get what you pay for with an Opc Supplement, sometimes less, and sometimes more.
- Product Reliability: How sturdy and durable an Opc Supplement is should be an indication of how long it will work out for you.
Romance University always remembers that maintaining Opc Supplement information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.
If you think that anything we present here regarding Opc Supplement is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly! We’re here for you all the time. Contact us here. Or You can read more about us to see our vision.