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The Best Differin Reviews of 2023 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best Differin Reviews of 2023. Check our ranking below.

2,894 Reviews Scanned

Rank No. #1
Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)
  • TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
  • CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
  • RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
  • DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
  • REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
Rank No. #2
Differin Acne Spot Treatment with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Treatment, Fast Acting Spot Treatment for Face, 1 oz
  • MAXIMUM STRENGTH 10% BENZOYL PEROXIDE: One 1 oz tube of Differin Acne Spot Treatment with 10% benzoyl peroxide as the strongest over-the-counter (OTC) concentration to visibly reduce acne size and redness after 1 use.
  • FAST BLEMISH SPOT TREATMENT: Penetrates deep into pores and works to immediately kill acne-causing bacteria
  • FOUR-IN-ONE ACNE TREATMENT FOR FACE: Acne solution that treats imperfections, prevents acne, targets acne-causing bacteria, and improves skin texture
  • FORMULATED WITH GLYCERIN: While benzoyl peroxide starts clearing acne blemishes, glycerin helps to minimize dryness
  • HOW TO USE: After cleansing with a gentle face wash, apply spot treatment on dry skin directly on affected areas, followed by moisturizer and SPF, and reapply as needed
SaleRank No. #3
Differin Acne Face Wash with 5% Benzoyl Peroxide, Daily Deep Cleanser by the makers of Differin Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 4 oz (Packaging May Vary)
  • TARGET ACNE: Penetrates deep into pores with 5% benzoyl peroxide with less irritation & dryness
  • DUAL-ACTION FORMULA: Micronized, dual-action formula absorbs excess oil in the skin, while releasing a gentle moisturizer that won't clog pores
  • KEY INGREDIENTS: 5% benzoyl peroxide that can effectively target and treat acne
  • HOW TO USE: Apply to dampened skin and gently massage, rinse thoroughly with warm water
  • DERMATOLOGIST-DEVELOPED: Can be used to effectively treat acne or maskne caused by wearing face masks or facial coverings
Rank No. #4
Differin Oil Absorbing Moisturizer with SPF 30, Sunscreen for Face by the makers of Differin Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 4 oz (Packaging May Vary)
  • SUN PROTECTION: Provides broad spectrum UVA/UVB SPF 30 protection as recommended by dermatologists for use with Differin Gel (0.1% Adapalene)
  • LIGHTWEIGHT & MATTIFYING: Formulated with Micropearl technology to absorb surface oil for a matte finish
  • DERMATOLOGIST-DEVELOPED: Oil-free, non-greasy, non-comedogenic, hypoallergenic and fragrance-free formula that won't clog pores
  • NOURISH & MOISTURIZE SKIN: Oleosome technology uses a low concentration of sunscreen filters for minimal irritation while providing significant hydration
  • HOW TO USE: Apply liberally 15 minutes before sun exposure and reapply at least every 2 hours
Rank No. #5
Differin Dark Spot Correcting Face Serum, Dark Spot Correcting Serum by the makers of Differin Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 1 oz (Packaging May Vary)
  • Differin Dark Spot Correcting Serum features 4% Niacinamide, a brightening ingredient that's clinically proven to reduce the appearance of dark spots and discoloration
  • GEL-LIKE FORMULA: Goes on smoothly and invisibly under makeup
  • SOOTHE & RENEW: Made with antioxidant sea buckthorn berry oil to help soothe skin and citric acid to help renew the skinÔøΩs surface
  • HOW TO USE: Apply to skin after cleansing. Use daily as needed, do not rinse off. If going outside, use a sunscreen, SPF 30 or higher
  • ADD TO YOUR REGIMEN: Gentle enough for daily use, morning or night and compatible with Differin Gel

Last update on 2025-07-21 / Affiliate links / Product Titles, Images, Descriptions from Amazon Product Advertising API

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FAQ:

Q: Does Differin help with blackheads?

A: Differin alone is most effective against blackheads and whiteheads, but if your acne is primarily pimples, cysts, or nodules, you may find that Differin is not enough to meet your needs. However, that doesn’t mean your only options are other retinoids, laden with unwanted side effects.

Q: Does Differin work on rosacea?

A: Differin is a brand name of Adapalene , traditionally used to try and combat acne, rather than rosacea. It came to my attention when I was looking around for other topical creams that might help limit my rosacea symptoms – As far as I can tell, I have papulopustular rosacea (the type with lots of spots in the usual rosacea places).

Q: Does Differin lighten skin?

A: Differin will make the skin look smooth and healthy. Additionally, Differin will actually help the discoloration left behind by previous acne breakouts. It will not make you more susceptible to scarring; in fact, it will prevent acne and therefore reduce any chance of scarring.

Q: Is there an alternative for Differin?

A: Differin Alternatives Compared. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Differin Remove Differin from your drug comparison. Doxycycline Remove Doxycycline from your drug comparison. Spironolactone Remove Spironolactone from your drug comparison. Add another drug to compare.

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