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The Best methyl guard plus of 2022 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best methyl guard plus of 2022. Check our ranking below.

2,004 Reviews Scanned

Rank No. #1
Thorne Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6, and B12 - Supports methylation and Healthy Level of homocysteine - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules
  • Healthy Methylation: Methyl-Guard Plus supports methylation and promotes a healthy level of homocysteine
  • Active Forms: Formulated with active folate (5-MTHF) and the active, tissue-ready forms of vitamins B2, B6, and B12 to optimize absorption
  • Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health
  • Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
  • Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
Rank No. #2
Thorne Methyl-Guard - Methylation Support Supplement with Folate and Vitamin B12-180 Capsules
  • Methylation: Support for healthy methylation*
  • Multiple Functions: Support for heart, blood vessel, brain, nerve, and bone health*
  • Homocysteine: Promotes homocysteine metabolism*
  • Active Bs: Contains the active, methylated forms of folate and vitamin B12 (5-MTHF and methylcobalamin)
  • Free From: Every Thorne product is made with the purest possible ingredients - without gluten or other major allergens (eggs, tree nuts, peanuts) This product also contains no soy, dairy, shellfish, or fish
SaleRank No. #3
Pure Therapro Rx Methyl B Complete - Optimal Methylated B Complex w/Quatrefolic 5-MTHF (Folate), Methylcobalamin (B12), B2, B6, & TMG, Active B Complex Manufactured in The USA - (120 Vegan Capsules)
  • ADVANCED FORMULA: The ultimate B complex vitamins for women and men alike, our Vitamin B complex provides essential B vitamins to support methylation processes. Featuring Folate as Quatrefolic for increased bioactivity, Betaine (also known as Trimethylglycine or TMG), and Vitamins B12 (Methylcobalamin and Adenosylcobalamin), B6, and B2, ours is a super B complex that provides vitamins essential for overall wellbeing, including energy production.
  • SIMPLY PURE INGREDIENTS: You absolutely won't find any fillers, excipients, or flow agents in these methyl B complex vegan supplements. Moreover, our Vitamin B supplements contain absolutely no gluten, wheat, soy, corn, yeast, animal products, nuts, artificial preservatives, sweeteners, or colors. We always promise to put quality first with absolutely no exceptions.
  • MANUFACTURED IN THE USA: Manufactured in NSF-certified facilities right here in the USA, our third-party tested B vitamin complex follows the FDA's strict cGMP guidelines. Each bottle of our B complex vitamin supplement contains sixty (60) capsules. Each capsule contains 25 mg Riboflavin, 15 mg Vitamin B6, 3,400 mcg Folate, 1,000 mcg Vitamin B12, and 650 mg TMG.
  • EASY TO TAKE B-COMPLEX VITAMIN SUPPLEMENTS: These vegan friendly vitamin B complex capsules are easy-to-swallow - Simply take one (1) or two (2) capsules with a meal/food daily or as directed by your qualified healthcare practitioner.
  • ABOUT US: Pure TheraPro Rx was founded in Denver Colorado to formulate and manufacture the highest quality supplements available on the market today. Purity is our priority, which is why we insist on using patented, clinically studied ingredients, and never utilizing fillers, flow agents, excipients, or ingredients sourced from China. We also never use dairy, gluten, corn, soy, or other common allergens in any of our class-leading, practitioner-recommended formulas.
Rank No. #4
Biote Nutraceuticals - METHYL FACTORS+ - Circulation + Mood (90 Capsules)
  • Promotes Normal Methylation
  • Supports a Healthy Heart
  • Encourages Energy & Focus
  • Soy Free, Dairy Free, Glutan Free
SaleRank No. #5
L Methyl Folate 15mg plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports Mood, Homocysteine Methylation, Cognition – Bioactive forms of Vitamin B9 & B12 (60 Capsules)
  • PROFESSIONAL STRENGTH: Provides clinically validated dosage of 15mg L Methyl folate in the 5-MTHF calcium salt form. This is the most active form of Folate.
  • ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
  • ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is crucial for those with methylation issues that cannot properly process folic acid.
  • BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
  • CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.
Rank No. #6
Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 & B6. Works Synergistically for Max Results-3 Month Supply
  • ♥ Lab tested and most powerful Methylfolate supplying essential support for DNA and neurotransmitter synthesis along with amino acid metabolism.
  • ♥ Developed as most optimally absorbed and bioavailable 5-MTHF
  • ♥ Delivering key supplementation for brain, heart and nerve function, as well as support for women who are pregnant and overall health
  • ♥ Suitable for people who are diagnosed with MTHFR mutation
  • ♥ To ensure purity and safety, our products are manufactured in a fully GMP-certified facility. Our product is third party tested to assure the quality and purity of each batch. All Made in USA.
Rank No. #7
Douglas Laboratories - Methyl B12 Plus - Supports Blood Cell Production, Nervous System, and Metabolism - 90 Lozenges
  • Energy Support: As coenzymes, the B vitamins play an important role in proper energy production, including the metabolism of lipids, carbohydrates, and proteins.*
  • Unique B Vitamins: Methylfolate and methylcobalamin are the predominant forms of B vitamins commonly found in cells that do not require additional conversion in the body.
  • Vitamins/Minerals/Amino Acids: Dietary supplement formulated to provide beneficial support in filling important nutrient gaps.*
  • Our uncompromising operational practices at our state-of-the-art manufacturing facilities surpass GMP standards and manufacturing regulations. All of our products are GMO-free.
  • For 65 years, Douglas Laboratories has been dedicated to meeting the needs of healthcare professionals. As a globally recognized leader in the development of innovative, science-based nutritional supplements, we strive to help healthcare professionals and their patients push their potential to live healthier, today and in the future.*
Rank No. #8
Neurobiologix Methyl Folate Plus™ Supplements - Bioactive Folinic Acid, Methyl Folate Dietary Capsules for Cardiovascular & Nervous System Health, Cell Growth and Tissue Repair (90 Capsules)
  • POWERFUL METHYL FOLATE SUPPLEMENT: Methyl Folate Plus dietary capsules support the issues associated with methylation and genetic enzymes. These professional grade supplements are free of gluten, soy, wheat, or any dairy products.
  • SUPPORTS CARDIOVASCULAR AND NERVOUS SYSTEMS: The greater bioavailability of folic acid compounds helps in enhancing the functioning of the heart, brain, and nerves. It also aids the immune system by keeping a healthy reserve of antibodies.
  • FASTER HEALING: A key component of these Methyl Folate capsules is Vitamin B2 Riboflavin-5-Phosphate. It helps in the development of tissues, neurotransmitters, cell growth and repair, and accelerated healing of injuries.
  • INCLUDES NIACINAMIDE (VITAMIN B3): As one of the crucial vitamins needed by the body, Niacinamide does not cause flushing at any dosage and helps to maintain energy levels, metabolism, and mitochondrial reactions.
  • RICH IN FOLINIC ACID: Derived from the vitamin folate, the folic acid supplements deliver the full spectrum of positive effects by converting the acid to their biologically active form: Vitamin B9/5-MTHF.
Rank No. #9
MethylPro 15mg L-Methylfolate (90 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF Supplement for Mood, Homocysteine Methylation + Immune Support, Gluten-Free with No Fillers
  • The Leader In Faster, Active Folate - Approximately half the US population may have difficulty converting folate into its active form. MethylPro is the leading nutraceutical line featuring l-methylfolate, the most advanced form for better results.*
  • Professional Strength - Many methylfolate products contain mcg or 1mg amounts. MethylPro offers a range of potent therapeutic doses. This 15 mg dose is our strongest, for a difference you can feel.*
  • Brain & Mood Support - Methylfolate is important for the production of neurotransmitters involved in concentration, sleep, energy, hormones and mood stability. This is the only form of folate to cross the blood-brain-barrier.*
  • Promotes Cardiovascular & Nerve Health - May help promote heart health & healthy peripheral nerve function by supporting already healthy homocysteine levels and nitric oxide production.*
  • No Fillers - MethylPro never uses fillers or excipients like bulking agents, glues, or binders. The only additional ingredient is the amino acid glycine. This product is free of soy, gluten, dairy, eggs, and nuts. Take only as directed under the supervision of a Physician.*
SaleRank No. #10
Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P, Dietary Supplement for Cellular Energy Metabolism and Cardiovascular Support, 100 Chewable Tablets, 100 Day Supply
  • Cellular Energy Metabolism and Cardiovascular support supplement*: Contains one 100 count bottle of Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg Chewable Tablets for a 100-day supply.
  • Offers a unique combination of B Vitamins in easy-to-take, lemon-flavored chewable tablets to support cellular energy metabolism, neurotransmitter synthesis and cardiovascular health.*
  • Dietary supplement with Methyl B12, Methyl Folate and Pyridoxal-5-Phosphate (P-5-P), the active forms of Vitamins B-12, B9 and B6.
  • Suggested Use: Adults, take one chewable tablet once a day or as directed by your qualified healthcare professional.
  • These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

Last update on 2023-01-10 / Affiliate links / Images from Amazon Product Advertising API

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