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The Best Methylfolate Supplement of 2023 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best Methylfolate Supplement of 2023. Check our ranking below.

2,573 (random number) Reviews Scanned

Rank No. #1

L Methyl Folate 15mg plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioactive forms of Vitamin B9 & B12 (60 Capsules)

PROFESSIONAL STRENGTH: Provides clinically validated dosage of 15mg L Methyl folate in the 5-MTHF calcium salt form. This is the most active form of Folate.
ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is crucial for those with methylation issues that cannot properly process folic acid.
BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.

SaleRank No. #2

NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets

CO-ENZYME B VITAMIN/1,000 mg TABLETS: Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA.
METABOLICALLY ACTIVE FOLATE/SUPERIOR BIOAVAILABLITY: Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian
GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
Packaged in the USA by a family owned and operated company since 1968

Rank No. #3

THORNE 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels - 60 Capsules - 5-MTHF 1mg

Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation*
Positivity: Supports a healthy outlook*
Nerves & Circulation: Supports healthy blood vessel and nerve function*
Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health*
Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams

SaleRank No. #4

Organic Methyl Folate 1000 mcg + Methyl B12 Cofactor (300 Servings) – Metabolically Active 5-MTHF Form, Organic Berry Flavor, Liquid Sublingual Form – Mood, Cognition, Methylation, Pregnancy (1oz)

BIOLOGICALLY ACTIVE FORM OF FOLATE (1 mg or 1000 mcg) : L-Methylfolate is the biological active form of Folate. It immediately absorbs into bloodstream and requires no processing by the body. The 1 mg dose is ideal to address daily Folate nutritional needs.*
ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.*
ENHANCED SUBLINGUAL ABSORPTION, CHERRY FLAVOR: The liquid sublingual form of L-methylfolate immediately absorbs directly the into bloodstream with higher overall absorption.*
SUPPORTS HEALTHY METHYLATION: The L Methyl Folate form of Folate is essential for healthy methylation especially for those with MTHFR gene.*
PREGNANCY, BRAIN, MOOD, ENERGY SUPPORT, CARDIOVASCULAR: 1 mg of Methylfolate supports healthy baby development during pregnancy. It is also essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.* Methylfolate also supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.*

SaleRank No. #5

L-METHYLFOLATE: A metabolically active form of Folic Acid, also known as Folate or B-9 Vitamin!
COMPLETE FORMULA: Quick-release capsules deliver 25,000 mcg Folate (15 mg L-METHYLFOLATE)
ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living.
CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO

Rank No. #6

Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets

Get a brain boost – Stay proactive about your brain health and support optimal cognitive function with this folate supplement. This 1700 mcg vitamin B formula helps maintain healthy cognition—especially as you age.
Pump up the heart health – This 5-MTHF supplement is a cardiovascular health superstar! Folate helps maintain already-normal homocysteine levels, an important cardiovascular health marker. Folate is a great way to keep heart health in check.
Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form.
Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.

Rank No. #7

Methylfolate 1,000mcg, 120 Capsules (Third Party Tested Methyl Folate Supplement) Methylated Folate is a More Active Form of Folate Than Folic Acid (Non-GMO, Vegan Safe) by Double Wood

METHYL FOLATE 1,000MCG VS FOLIC ACID 1,000MCG - Recent research suggests that l methylfolate is a more active form of folate when compared to folic acid. Folic acid is the synthetic form of Folate
METABOLICALLY ACTIVE 5-MTHF (OPTIMZED FOLATE) - L Methyl Folate is the biological and active form of folate. It is more immediately absorbed into the bloodstream and requires little processing by the body
METHYLFOLATE vs METHYL B12 - Methyl folate and Methyl B12 are both metabolically active forms of B Vitamins and are far more bioavailable when compared to their non-methylated counterparts
VEGAN SAFE, Manufactured in the USA from Globally Sourced Ingredients, NON-GMO, GLUTEN FREE - Double Wood's L Methylfolate capsules are vegan safe, Manufactured in the USA from Globally Sourced Ingredients, Gluten Free, and Non-GMO
SATIFSACTION ASSURED - If you aren't happy with the product for any reason please contact us and we promise to make things right

Rank No. #8

Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 B6. Works Synergistically for Max Results-3 Month Supply

♥ Lab tested and most powerful Methylfolate supplying essential support for DNA and neurotransmitter synthesis along with amino acid metabolism.
♥ Developed as most optimally absorbed and bioavailable 5-MTHF
♥ Delivering key supplementation for brain, heart and nerve function, as well as support for women who are pregnant and overall health
♥ Suitable for people who are diagnosed with MTHFR mutation
♥ To ensure purity and safety, our products are manufactured in a fully GMP-certified facility. Our product is third party tested to assure the quality and purity of each batch. All Made in USA.

Rank No. #9

MethylPro 15mg L-Methylfolate - Professional Strength Active Methyl Folate Supplement for Brain Support, Balanced Mood + Immune Health - Gluten-Free with No Fillers (90 Capsules)

Mood + Cardiovascular Support - Our L methylfolate 15mg supplement is our strongest dose, and may help promote normal serotonin, norepinephrine, and dopamin production. It can help your body convert homocysteine to methionine, and produce key neurotransmitters for mood support.*
Heightened Bioavailability - Our Methyl Folate supplement contains a more active, bioavailable form of folate b vitamins. It is the only form to cross the blood-brain-barrier, and can provide the most effective form of folate for those with genetic MTHFR variations.*
Take The Right Kind Of Folate - About half of the US population have a reduced ability to convert folic acid to 5 MTHF, the activated form of folate. Taking methylated b vitamins like our 5 mthf supplement can help support direct vitamin absorption.*
Filler-Free Nerve Support - This cognitive supplement can offer daily brain support, and promote healthy mood, cardio, and nerve function. It contains l-methylfolate that is free of fillers, binders, preservatives, artificial colors + flavors.*
Physician's Choice - The health care professional's choice for quality supplements since 1984. We utilize current research, clinical studies, and third-party testing at all stages of development. An L-Methylfolate 15 mg supplement you can trust, at an exceptional value.*

SaleRank No. #10

Jarrow Formulas Extra Strength Methyl Folate 400 mcg, Dietary Supplement for Cardiovascular and Neurologic Health Support, 60 Veggie Capsules, 60 Day Supply

Cardiovascular and Neurologic Health support supplement: Contains one 60 count bottle of Jarrow Formulas Extra Strength Methyl Folate 400 mcg Veggie Capsules for a 60-day supply
Dietary supplement with 400 mcg of Methyl Folate (5-MTHF), a biologically active form of Vitamin B9 to support cardiovascular health, proper cell division and neurologic health*
Features Quatrefolic methyl folate that can cross the blood-brain barrier*
Suggested Use: Adults, take one capsule once a day with or without food, or as directed by your qualified healthcare professional
These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

SaleRank No. #11

NOW Supplements, Methyl Folate 5000 mcg, Superior Bioavailability, 50 Veg Capsules

Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA.
Unlike regular folic acid, methylfolate has been shown to penetrate the blood-brain barrier, where it helps to support neurological health.
Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
Quatrefolic
A Dietary Supplement

Rank No. #12

THORNE 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels - 60 Capsules - 5-MTHF 5mg

Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation*
Positivity: Supports a healthy outlook*
Nerves & Circulation: Supports healthy blood vessel and nerve function*
Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health*
Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams

Rank No. #13

Gluten Free, Non-GMO; Free Of Wheat, Yeast, Milk, Lactose, Soy, Artificial Color, Artificial Flavor
Each L-Methylfolate capsule provides you with 1000 mcg of this bioavailable form of folic acid
Folate, also referred to as Folic Acid, is a fully active B complex vitamin
Our professional formula is backed by our commitment to purity and potency
Manufactured in a facility that undergoes is GMP certified.

Rank No. #14

L-METHYLFOLATE: A metabolically active form of Folic Acid, also known as Folate or B-9 Vitamin
COMPLETE FORMULA: Quick-release capsules deliver 12,500 mcg Folate (7.5 mg L-METHYLFOLATE)
ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO

SaleRank No. #15

Pure Folate 400mcg, Optimized Methylfolate, Clean Label, 180 Small Tablets, Lab Verified, Vegan & Hypoallergenic, Supplement for Men & Women, Pregnancy, Mood, & Heart Health, by Igennus

BIOACTIVE FORM: L-methylfolate is the metabolically active form of folate, the preferred form for those with SNPs on folate genes, raising levels 1.8x higher than folic acid*
OPTIMAL DAILY DOSE: expertly formulated to provide an effective dose of folate in the body-ready and fully methylated form, without overloading the body. Each bottle provides 180 small 1-a-day tablets
PREGNANCY, HEART & MOOD SUPPORT: folate supports mood & brain function, blood formation, homocysteine metabolism & amino acid synthesis. Pregnancy increases folate requirements with low status a risk factor for neural tube defects*
PURE & CLEAN: lab-verified, vegan, non-GMO, hypoallergenic ingredients with no unpleasant additives (no silicon dioxide or, magnesium stearate)
SUPPLEMENTS YOU CAN TRUST: expertly formulated by Igennus nutrition scientists and our resident medical doctor, lab verified to ensure the highest quality

Rank No. #16

Codeage Methylfolate B Complex Supplements - 5 MTHF, Methylcobalamin 1000mcg Methylated Vitamin B12, Riboflavin, Betaine, Vitamins B6, Methylation Cycle MTHFR - 2 Months - 120 Capsules

MTHF supplement: Methylfolate B Complex offers an all-in-one methylation supplement with folate, methylated vitamins, riboflavin, and betaine in an easy to use capsule format.
Folate & riboflavin: 1360 mcg of 5- MTHF folate with Quatrefolic 5 methylfolate and glucosamine salt as a folate supplement. This methylation formula also contains 30 mg of Riboflavin 5’- Phosphate as a riboflavin supplement.
Betaine: The blend features 600 mg of betaine as trimethylglycine (TMG).
Methylated vitamins: Codeage Methylfolate B Complex can provide an active, methylated forms of folate and vitamins B2, B6, B12 (5-MTHF and methylcobalamin B12). The vitamins included in this formula (vitamin B6 and vitamin B12 1000 mcg) are also provided in their phosphorylated forms.*
Vegan, gluten free, non-GMO, & made in USA: Codeage Methylfolate B Complex supplement is vegan, and non-GMO. This formula is also gluten, dairy, and soy free. Codeage methylated vitamins capsules are manufactured in the USA in an cGMP certified facility and third party tested. 2 months supply.

SaleRank No. #17

ESSENTIAL NUTRIENT: Methyl Folate is the active, more bioavailable form of the B-Vitamin Folic Acid
CONVENIENT FORM: Delivers 1000 mcg of this important nutrient in Quick-Release capsules
EXPERTLY CRAFTED: Specially formulated supplement derived from high-quality sourcing standards
HORBAACH MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
NATURALLY FREE OF: Gluten, Wheat, Yeast, Milk, Lactose, Soy, Artificial Color & Flavoring & NON-GMO

SaleRank No. #18

METHYLFOLATE SUPPLEMENT 5-MTHF Supplement (200 Servings 1700 DFE) Methylated B9 Vitamin, Active Folic Acid/Methylated Folate Supplement Drops

WHAT IS METHYLATED FOLATE? Methylated Folate, also known as 5-MTHF (5-methyltetrahydrofolate), is the active form of Vitamin B9 that the body can immediately use without conversion.
MTHFR MUTATION: For individuals with genetic variations like the MTHFR mutation, the body's ability to process standard Folic Acid is hindered. Methylfolate, being a methylated and already active version of Folate, circumvents this conversion challenge
JUST METHYLFOLATE: Oral Absorption for easy dosaging and intake
200 SERVINGS: Safe for adults to children/kids. A 7 mg and 15 mg dosages which is very high. Unless recommended by your doctor, starting at less than 1 MG (1000 mcg) and then re-assessing is much more sensible
LIGHT STRAWBERRY NATURAL FLAVOR: Simple Ingredients with no artifical flavors or colors. Zero Sugar

Rank No. #19

Bluebonnet Earth Sweet Cellular Active Methylfolate 400 mcg Chewable Tablets, 90 Count

Contains 400 mcg of the methylated form of Folate, L-Methylfolate in raspberry flavored chewable tablets sweetened with EarthSweet QuatreFolic is a patented form of 5-MTHF - also known as 5-methyltetrahydrofolate
Metabolically Active Folate Healthy Neurological Development
90 Chewable Tablets, 90 Servings
Soy-Free, Gluten-Free, Non-GMO, Kosher Certified, Dairy-Free, Vegan
Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of yeast, gluten, barley, rice and sodium.

Rank No. #20

Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets

NEW LABEL; SAME GREAT FORMULA. The formula is the same, but because of changes in Folate labeling requirements, the label has changed to reflect the bio-availability of folate. 5-MTHF is 1.7 times more bioavailable than naturally occurring folate, so the newer label lists 1700 mcg DFE (Dietary Folate Equivalents).
Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets
Superior formulation: More bioavailablity than ordinary folic acid supplements
Helps maintain healthy homocysteine levels already within the normal range.
Non-GMO. Add to your cart because you deserve the best.

Last update on 2024-06-08 / Affiliate links / Product Titles, Images, Descriptions from Amazon Product Advertising API

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Is it worth buying an Methylfolate Supplement?
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Potential sources can include buying guides for Methylfolate Supplement, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible Methylfolate Supplement. Make sure that you are only using trustworthy and credible websites and sources.

We provide an Methylfolate Supplement buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information. How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available Methylfolate Supplement currently available on the market.

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Brand Value: Every brand of Methylfolate Supplement has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
Features: What bells and whistles matter for an Methylfolate Supplement?
Specifications: How powerful they are can be measured.
Product Value: This simply is how much bang for the buck you get from your Methylfolate Supplement.
Customer Ratings: Number ratings grade Methylfolate Supplement objectively.
Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their Methylfolate Supplement.
Product Quality: You don’t always get what you pay for with an Methylfolate Supplement, sometimes less, and sometimes more.
Product Reliability: How sturdy and durable an Methylfolate Supplement is should be an indication of how long it will work out for you.

We always remember that maintaining Methylfolate Supplement information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

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FAQ:

Q: What is methylfolate good for?

A: Methylfolate can be highly effective for helping with depression and other mental health issues. It is particularly effective because it can be carried through the blood-brain barrier to aid with neurotransmitters , mood regulation, and other brain functions.

Q: What is methylfolate prescribed for?

A: Methylfolate is vital to DNA synthesis and detoxifying homocysteine. It may also enhance an assortment of mental disorders such as depression and schizophrenia. It’s usually utilized to slow cognitive decline that’s observed in several mental disorders, such as Alzheimer’s, mania, and depression.

Q: Why is taking folic acid so important?

A: Folic acid helps your body produce and maintain new cells , and also helps prevent changes to DNA that may lead to cancer. As a medication, folic acid is used to treat folic acid deficiency and certain types of anemia (lack of red blood cells) caused by folic acid deficiency.

Q: What is methylfolate used for?

A: Methylfolate is a supplement form of the essential nutrient called folate (vitamin B9). It is one of the essential nutrients that many people are deficient in for dietary and genetic reasons. L-methylfolate is used for DNA synthesis (a process we all must go through all the time).