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The Best Methylfolate Supplement of 2023 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best Methylfolate Supplement of 2023. Check our ranking below.

2,563 Reviews Scanned

SaleRank No. #1

NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets

CO-ENZYME B VITAMIN/1,000 mg TABLETS: Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA.*
METABOLICALLY ACTIVE FOLATE*/SUPERIOR BIOAVAILABLITY: Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian
GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
Packaged in the USA by a family owned and operated company since 1968

Rank No. #2

Thorne 5-MTHF 1mg - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels - 60 Capsules

Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation*
Positivity: Supports a healthy outlook*
Nerves & Circulation: Supports healthy blood vessel and nerve function*
Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health*
Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams

Rank No. #3

Organic Methyl Folate 1000 mcg + Methyl B12 Cofactor (300 Servings) – Metabolically Active 5-MTHF Form, Organic Berry Flavor, Liquid Sublingual Form – Mood, Cognition, Methylation, Pregnancy (1oz)

SaleRank No. #4

L-METHYLFOLATE: A metabolically active form of Folic Acid, also known as Folate or B-9 Vitamin!
COMPLETE FORMULA: Quick-release capsules deliver 25,000 mcg Folate (15 mg L-METHYLFOLATE)
ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living.
CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO

Rank No. #5

Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 B6. Works Synergistically for Max Results-3 Month Supply

♥ Lab tested and most powerful Methylfolate supplying essential support for DNA and neurotransmitter synthesis along with amino acid metabolism.
♥ Developed as most optimally absorbed and bioavailable 5-MTHF
♥ Delivering key supplementation for brain, heart and nerve function, as well as support for women who are pregnant and overall health
♥ Suitable for people who are diagnosed with MTHFR mutation
♥ To ensure purity and safety, our products are manufactured in a fully GMP-certified facility. Our product is third party tested to assure the quality and purity of each batch. All Made in USA.

SaleRank No. #6

Jarrow Formulas Extra Strength Methyl Folate 400 mcg, Dietary Supplement for Cardiovascular and Neurologic Health Support, 60 Veggie Capsules, 60 Day Supply

Cardiovascular and Neurologic Health support supplement: Contains one 60 count bottle of Jarrow Formulas Extra Strength Methyl Folate 400 mcg Veggie Capsules for a 60-day supply
Dietary supplement with 400 mcg of Methyl Folate (5-MTHF), a biologically active form of Vitamin B9 to support cardiovascular health, proper cell division and neurologic health*
Features Quatrefolic methyl folate that can cross the blood-brain barrier*
Suggested Use: Adults, take one capsule once a day with or without food, or as directed by your qualified healthcare professional
These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

Rank No. #7

Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets

Get a brain boost – Stay proactive about your brain health and support optimal cognitive function with this folate supplement. This 1700 mcg vitamin B formula helps maintain healthy cognition—especially as you age.
Pump up the heart health – This 5-MTHF supplement is a cardiovascular health superstar! Folate helps maintain already-normal homocysteine levels, an important cardiovascular health marker. Folate is a great way to keep heart health in check.
Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form.
Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.

SaleRank No. #8

ESSENTIAL NUTRIENT: Methyl Folate is the active, more bioavailable form of the B-Vitamin Folic Acid
CONVENIENT FORM: Delivers 1000 mcg of this important nutrient in Quick-Release capsules
EXPERTLY CRAFTED: Specially formulated supplement derived from high-quality sourcing standards
HORBAACH MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
NATURALLY FREE OF: Gluten, Wheat, Yeast, Milk, Lactose, Soy, Artificial Color & Flavoring & NON-GMO

Rank No. #9

L Methyl Folate 15mg plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports Mood, Homocysteine Methylation, Cognition – Bioactive forms of Vitamin B9 & B12 (60 Capsules)

PROFESSIONAL STRENGTH: Provides clinically validated dosage of 15mg L Methyl folate in the 5-MTHF calcium salt form. This is the most active form of Folate.
ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is crucial for those with methylation issues that cannot properly process folic acid.
BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.

Rank No. #10

MethylPro 15mg L-Methylfolate (30 Capsules) - Professional Strength Active Methylfolate, 5-MTHF Supplement for Mood, Brain Health + Immune Support, Non-GMO + Gluten-Free with No Fillers

Active Methylfolate - Approximately half the US population may have difficulty converting folate into its active form. MethylPro is the leading nutraceutical line featuring l methylfolate, the most advanced form for better results.*
Professional Strength Folate Capsules - MethylPro offers a range of potent therapeutic doses depending on your personal goals. This l-methylfolate 15 mg dose is our strongest, for a difference you can feel.*
Mood & Brain Support - Methylated folate is important for the production of neurotransmitters involved in concentration, sleep, energy, hormones and mood stability. This is the only form of folate to cross the blood-brain-barrier.*
Cardiovascular & Nerve Health - L- methylfolate may support heart & brain health by promoting already healthy peripheral nerve function and nitric oxide production.*
No Fillers - MethylPro's 15 mg methylfolate is free of bulking agents and binders. This folate supplement for women and men contains no soy, gluten, dairy, eggs, and nuts. Take only as directed under the supervision of a Physician.*

Rank No. #11

BlueBonnet Earth Sweet Cellular Active Methylfolate 400 mcg Chewable Tablets, 90 Count

Contains 400 mcg of the methylated form of Folate, L-Methylfolate in raspberry flavored chewable tablets sweetened with EarthSweet QuatreFolic is a patented form of 5-MTHF - also known as 5-methyltetrahydrofolate
Metabolically Active Folate Healthy Neurological Development
90 Chewable Tablets, 90 Servings
Soy-Free, Gluten-Free, Non-GMO, Kosher Certified, Dairy-Free, Vegan
Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of yeast, gluten, barley, rice and sodium.

Rank No. #12

Superior Source Methylfolate 5-MTHF 1000 mcg, Quick Dissolve Sublingual Tablets, 60 Ct, Biologically Active Form of Folate, Cardiovascular Health, Energy Metabolism & Prenatal Development, Non-GMO

HEART HEALTH and PRENATAL DEVELOPMENT – Folate is a member of the B-Complex and it plays an important role in prenatal development and supports cardiovascular health. Methylfolate is the biologically active, naturally occurring form of folate suitable for people who are diagnosed with MTHFR mutation. Also, in addition to helping maintain homocysteine levels, it plays a significant role in supporting a healthy nervous system and the health of red blood cells.
JUST PURE INGREDIENTS – Non-GMO, gluten-free, preservative free, sugar free, dye free; no fillers, no additives, no excipients, no Magnesium Stearate or Silica. Other vitamins require lots of binders to hold them together. Our Micro tablets only contain the pure active nutrients and other necessary natural ingredients.
MICROLINGUAL VITAMINS – Melts that dissolve instantly with no pills to swallow. Superior Source pioneered the world's best delivery system of sublingual vitamins that melt fast under the tongue and give maximum absorption for the body.
GMP CERTIFIED QUALITY - We test all incoming raw materials for the active ingredients, heavy metals, GMOs, and microbial contamination through a third-party certified laboratory. Once manufactured, the Superior Source MicroLingual tablets go for additional potency, contaminant and purity testing. Once we confirm that the finished product meets or exceeds our GMP compliant quality standards it is released to you.
SUPERIOR SOURCE, THE COMPANY THAT CARES - Creating pure MicroLingual vitamins since 1998 in our family owned manufacturing facility. We are a company built from love for health, wellness, fitness, nutrition, and the need for a better life.

SaleRank No. #13

Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P, Dietary Supplement for Cellular Energy Metabolism and Cardiovascular Support, 100 Chewable Tablets, 100 Day Supply

Cellular Energy Metabolism and Cardiovascular support supplement*: Contains one 100 count bottle of Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg Chewable Tablets for a 100-day supply.
Offers a unique combination of B Vitamins in easy-to-take, lemon-flavored chewable tablets to support cellular energy metabolism, neurotransmitter synthesis and cardiovascular health.*
Dietary supplement with Methyl B12, Methyl Folate and Pyridoxal-5-Phosphate (P-5-P), the active forms of Vitamins B-12, B9 and B6.
Suggested Use: Adults, take one chewable tablet once a day or as directed by your qualified healthcare professional.
These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

Rank No. #14

Designs for Health L-5-MTHF Folate, 500mcg (850mcg DFE) - Quatrefolic Active Vitamin B9 Methylfolate Supplement - Non-GMO, Gluten Free (120 Capsules)

Bio-Active Folate - This product contains 5-methyltetrahydrofolate, the natural, active form of folate found in the body. It is also one of several forms found in food.*
500mcg Per Capsule - Each capsule contains 500mcg of 5-methyltetrahydrofolate (or 850mcg DFE / Dietary Folate Equivalent). Organic spinach powder gives the capsules their green color.*
Premium Patented Form - Our L-5-MTHF uses an innovative, patented folate derivative which has demonstrated high bioavailability and solubility, as well as long-lasting stability. *
Vegetarian & Non-GMO - This product is Vegetarian-Friendly. Made without GMOs, Soy, Gluten, or Dairy.*
Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

SaleRank No. #15

NatureBell L Methylfolate 15mg (5-MTHF) with Methyl B12 1000mcg, 180 Vegetarian Capsules | High Potency Dual Action for Energy & Cognitive Support, Active Folic Acid - Methyl Folate Supplement

High Potency Dual Action: Powerful combination of Methyl Folate 15mg and Vitamin B12 for enhanced energy and cognitive support, promoting overall health and well-being.
Active Folic Acid - L-methylfolate: Easily absorbed for maximum benefits in mental clarity, cognitive function, prenatal health.
180 Vegetarian Capsules: 6-month supply of premium quality, gluten-free, non-GMO vegetarian capsules, suitable for those with dietary restrictions.
Energy & Cognitive Health: Supports normal energy metabolism, reduces fatigue, and maintains healthy neurological function for optimal mental performance and focus.
Trusted Quality & Purity: Certified by 3rd party labs, ensuring the highest quality standards and ingredient purity for a premium and effective supplement.

Rank No. #16

Thorne 5-MTHF 5mg - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels - 60 Capsules

Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation*
Positivity: Supports a healthy outlook*
Nerves & Circulation: Supports healthy blood vessel and nerve function*
Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health*
Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams

Rank No. #17

MethylPro 5mg L-Methylfolate (30 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF Supplement for Mood, Homocysteine Methylation + Immune Support, Gluten-Free with No Fillers

Take The Right Kind Of Folate - About half of the US population have a reduced ability to convert folic acid to 5-MTHF, the activated form of folate. Taking methylated b vitamins such as l- methylfolate can support direct vitamin absorption.*
Bioavailable Mood Support - Our L-Methylfolate is a more active, bioavailable form of folate b vitamins. It is the only form of folate to cross the blood-brain-barrier.*
Nerve & Mood Support - Methylated folate is a brain supplement necessary for the production of the neurotransmitters serotonin, norepinephrine, and dopamine, which are important for nerve maintenance.*
Purity, Quality, Potency - Our l-methylfolate is free of fillers, binders, preservatives, artificial colors + flavors. No gluten, egg, peanuts, tree nuts, or magnesium stearate goes into our methylated b vitamins. Bottles are BPA-free recycled amber.
Physician's Choice - The health care professional's choice for quality supplements since 1984. We utilize current research, clinical studies, and third-party testing at all stages of development. Methyl folate you can trust, at an exceptional value.

SaleRank No. #18

Nutricost Methyl Folate 1000mcg, 120 Vegetarian Capsules - Gluten Free, Non-GMO

120 Capsules Methyl Folate (120 Servings)
1,000mcg Methyl Folate Per Serving
Vegetarian Capsules
Non-GMO & Gluten Free & 3rd Party Tested
Made in a GMP Compliant, FDA Registered Facility

Rank No. #19

Best Naturals Methyl Folate 15000 mcg (15mg) (Most Bio-Available) 60 Tablets - Supports Cell Formation Growth Function, Brain, Memory, Cardiovascular Health (60 Count (Pack of 1))

PREMIUM FORMULA - Our Methyl Folate (5-MTHF) Supplements is the most active form, stable & bio available of Folic Acid Supplement.*
3rd Part Lab Tested - Our All Best Naturals Products come with 3rd Party Independent Lab Tested
Supports Cell Formation Growth Function, Brain, Memory, Cardiovascular Health*
No Artiﬁcial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Corn, No Soy, No Egg, No Lactose, No Gluten, No Wheat, No Yeast, No Fish, No Sodium.
TOP QUALITY GMP CERTIFIED PRODUCTS - All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency.

Rank No. #20

L-METHYLFOLATE: A metabolically active form of Folic Acid, also known as Folate or B-9 Vitamin
COMPLETE FORMULA: Quick-release capsules deliver 12,500 mcg Folate (7.5 mg L-METHYLFOLATE)
ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO

Last update on 2023-07-29 / Affiliate links / Product Titles, Images, Descriptions from Amazon Product Advertising API

How Do You Buy The Best Methylfolate Supplement?

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We’ve done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for Methylfolate Supplement that you consider buying. Your questions might include the following:

Is it worth buying an Methylfolate Supplement?
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Why is it crucial to invest in any Methylfolate Supplement, much less the best one?
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We’re convinced that you likely have far more questions than just these regarding Methylfolate Supplement, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for Methylfolate Supplement, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible Methylfolate Supplement. Make sure that you are only using trustworthy and credible websites and sources.

We provide an Methylfolate Supplement buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information. How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available Methylfolate Supplement currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

Brand Value: Every brand of Methylfolate Supplement has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
Features: What bells and whistles matter for an Methylfolate Supplement?
Specifications: How powerful they are can be measured.
Product Value: This simply is how much bang for the buck you get from your Methylfolate Supplement.
Customer Ratings: Number ratings grade Methylfolate Supplement objectively.
Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their Methylfolate Supplement.
Product Quality: You don’t always get what you pay for with an Methylfolate Supplement, sometimes less, and sometimes more.
Product Reliability: How sturdy and durable an Methylfolate Supplement is should be an indication of how long it will work out for you.

We always remember that maintaining Methylfolate Supplement information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding Methylfolate Supplement is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly! We’re here for you all the time. Contact us here. Or You can read more about us to see our vision.

FAQ:

Q: What is methylfolate good for?

A: Methylfolate can be highly effective for helping with depression and other mental health issues. It is particularly effective because it can be carried through the blood-brain barrier to aid with neurotransmitters , mood regulation, and other brain functions.

Q: What is methylfolate prescribed for?

A: Methylfolate is vital to DNA synthesis and detoxifying homocysteine. It may also enhance an assortment of mental disorders such as depression and schizophrenia. It’s usually utilized to slow cognitive decline that’s observed in several mental disorders, such as Alzheimer’s, mania, and depression.

Q: Why is taking folic acid so important?

A: Folic acid helps your body produce and maintain new cells , and also helps prevent changes to DNA that may lead to cancer. As a medication, folic acid is used to treat folic acid deficiency and certain types of anemia (lack of red blood cells) caused by folic acid deficiency.

Q: What is methylfolate used for?

A: Methylfolate is a supplement form of the essential nutrient called folate (vitamin B9). It is one of the essential nutrients that many people are deficient in for dietary and genetic reasons. L-methylfolate is used for DNA synthesis (a process we all must go through all the time).