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The Best cold and flu tablets of 2022 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best cold and flu tablets of 2022. Check our ranking below.

2,587 Reviews Scanned

SaleRank No. #1
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
  • 24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. From the doctor recommended pain relief brand, the combo pack includes 16 Daytime and 8 Nighttime caplets for relief any time of the day
  • The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
  • The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion and pressure
  • Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
  • The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine.
Rank No. #2
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count
  • ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
  • EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
  • COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
  • COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
  • MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu
Rank No. #3
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)
  • ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu
  • NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains
  • NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains
  • PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat
  • COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help
Rank No. #4
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
  • RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
  • POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
  • NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
  • PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
SaleRank No. #5
Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct
  • Twin 2 Pack of 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
Rank No. #6
Advil Multi Symptom Cold and Flu Medicine, Cold Medicine for Adults with Ibuprofen, Phenylephrine HCL and Chlorpheniramine Maleate - 50 Coated Tablets
  • Fifty packets of 1 coated tablet of Advil Multi Symptom Cold and Flu Medicine, Cold Medicine for Adults with Ibuprofen, Phenylephrine HCL and Chlorpheniramine Maleate
  • Powerful Ibuprofen 200mg, chlorpheniramine maleate 4mg and phenylephrine HCL 10 mg tablets for multi-symptom relief
  • Uniquely formulated to fight common cold and flu symptoms, providing nasal congestion, nasal swelling, sneezing, sinus pressure, headache, fever, body aches and runny nose relief
  • Cold medicine for adults available in easy-to-take coated tablet form - the perfect addition to your college dorm room essentials
  • For use by people 12 years of age and older
SaleRank No. #7
Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)
  • Nature's Way Cold+Flu Relief provides cold and flu symptom relief with a multi-action formula for body aches, congestion, cough, fever, runny nose, and sore throat.
  • Non-drowsy formula with clinically proven Pelargonium sidoides 1X to shorten duration and reduce severity of common cold symptoms and throat, nasal, bronchial irritations, plus Alpha-CF to reduce flu symptoms.
  • Children 6-12 years of age, chew one tablet two times daily. Adults and children 13 years of age and older chew one tablet three times daily. Delicious berry flavored chewables can be taken whenever you need relief, combining Pelargonium sidoides 1X and Alpha CF into one great-tasting formula.
  • Made with a proprietary Pelargonium sidoides 1X and Alpha CF.
  • At Nature’s Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness.
Rank No. #8
Contac Non-Drowsy Day & Multi-Symptom Night Cold & Flu Medicine, Maximum Strength Relief for Fever, Sore Throat, Nasal Congestion, Head & Body Aches, Runny Nose, 28 Count, 16 Day, 12 Night Caplets
  • FAST-ACTING, MAXIMUM-STRENGTH RELIEF: Get 24-hour relief from common cold & flu symptoms, including nasal congestion, sinus congestion and pressure, sore throat, head & body aches and fever, runny nose, and sneezing
  • NON-DROWSY, DAYTIME RELIEF: Our severe cold & flu medicine provides symptom relief without making you drowsy; Stay alert and active throughout your day
  • NIGHTTIME COMFORT: Sleep better with our nighttime formula that eases symptoms for restful sleep
  • 24-HOUR RELIEF: Feel better and stay alert by using our daytime formula with Phenylephrine HCI a nasal decongestant to ease congestion and acetaminophen a pain reliever/fever reducer to relieve minor aches, pains and sore throat; get some rest at night with our nighttime formula that also contains Chlorpheniramine maleate an antihistamine to ease your symptoms overnight
  • FIGHT THE FLU & COLD: Contac Cold + Flu tackles severe cold & flu symptoms for adults and children 12 years and older; FSA/HSA eligible, gluten-free and no artificial colors
Rank No. #9
Advil Multi Symptom Cold and Flu Medicine, Cold Medicine for Adults with Ibuprofen, Phenylephrine HCL and Chlorpheniramine Maleate - 20 Coated Tablets
  • One bottle of 20 coated tablets of Advil Multi Symptom Cold and Flu Medicine, Cold Medicine for Adults with Ibuprofen, Phenylephrine HCL and Chlorpheniramine Maleate
  • Powerful Ibuprofen 200mg, chlorpheniramine maleate 4mg and phenylephrine HCL 10 mg tablets for multi-symptom relief
  • Uniquely formulated to fight common cold and flu symptoms, providing nasal congestion, nasal swelling, sneezing, sinus pressure, headache, fever, body aches and runny nose relief
  • Cold medicine for adults available in easy-to-take coated tablet form - the perfect addition to your college dorm room essentials
  • For use by people 12 years of age and older
SaleRank No. #10
GenCare - Multi Symptom Non Drowsy Daytime Cold & Flu Relief Acetaminophen 325mg, Dextromethorphan HBr 10mg, Phenylephrine HCl 5mg (48 Softgels) Non Habit Forming Pain Reliever & Nasal Decongestant
  • POWERFUL MULTI SYMPTOM RELIEF - Each serving contains 325mg of Acetaminophen (Pain reliever/fever reducer), Dextromethorphan HBr 10mg (Cough suppressant) and Phenylephrine HCl 5mg (Nasal decongestant). Compare to generic Dayquil active ingredients.
  • NON DROWSY FORMULA - Enjoy non habit forming, non-drowsy any time of day relief. Temporarily relieves common cold/flu symptoms: nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever. Do not use with any other drug containing acetaminophen.
  • BEST VALUE - GenCare Cold & Flu lets you stock up and save big compared to retail pharmacies and big box stores. Order your value savings bottle from the comfort of your own home while sick or recovering. Store at room temperature.
  • DIRECTIONS: do not take more than directed (see OVERDOSE WARNING) do not exceed 4 doses per 24 hrs. Adults and children 12 years of age or older: take 2 softgels with water every 4 hrs. Children 6 to under 12 years: ask a doctor. Children 6 years under: do not use.
  • 100% SATISFACTION GUARANTEE - We know you and your family will love the ultimate convenience of our non habit forming daytime cold and flu relief. That's why we back up each tamper proof bottle with our 100% Satisfaction Guarantee. Join thousands of customers...Click Add-to-Cart Today!

Last update on 2025-06-12 / Affiliate links / Images from Amazon Product Advertising API

How Do You Buy The Best cold and flu tablets?

Do you get stressed out thinking about shopping for a great cold and flu tablets? Do doubts keep creeping into your mind? We understand, because we’ve already gone through the whole process of researching cold and flu tablets, which is why we have assembled a comprehensive list of the greatest cold and flu tablets available in the current market. We’ve also come up with a list of questions that you probably have yourself.

We’ve done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for cold and flu tablets that you consider buying. Your questions might include the following:

  • Is it worth buying an cold and flu tablets?
  • What benefits are there with buying an cold and flu tablets?
  • What factors deserve consideration when shopping for an effective cold and flu tablets?
  • Why is it crucial to invest in any cold and flu tablets, much less the best one?
  • Which cold and flu tablets are good in the current market?
  • Where can you find information like this about cold and flu tablets?

We’re convinced that you likely have far more questions than just these regarding cold and flu tablets, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for cold and flu tablets, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible cold and flu tablets. Make sure that you are only using trustworthy and credible websites and sources.

We provide an cold and flu tablets buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information. How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available cold and flu tablets currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of cold and flu tablets has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an cold and flu tablets?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your cold and flu tablets.
  5. Customer Ratings: Number ratings grade cold and flu tablets objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their cold and flu tablets.
  7. Product Quality: You don’t always get what you pay for with an cold and flu tablets, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an cold and flu tablets is should be an indication of how long it will work out for you.

We always remember that maintaining cold and flu tablets information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding cold and flu tablets is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly! We’re here for you all the time. Contact us here. Or You can read more about us to see our vision.

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