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The Best gaming mouse programmable buttons of 2022 – Reviewed and Top Rated

After hours researching and comparing all models on the market, we find out the Best gaming mouse programmable buttons of 2022. Check our ranking below.

2,186 Reviews Scanned

SaleRank No. #1
EVGA X15 MMO Gaming Mouse, 8k, Wired, Black, Customizable, 16,000 DPI, 5 Profiles, 20 Buttons, Ergonomic 904-W1-15BK-KR
  • USB2.0 High-Speed 32-bit Arm Cortex-M33 core microprocessor, supporting a native 8K Hz report rate. Eight times the standard 1K Hz on competing gaming mice for faster response time and precise movements
  • Light Strike LK Optical switches are designed to provide faster and better stability. The switches are quicker than any mechanical switch and more durable, reaching a life span of 70 million clicks
  • 5 customizable onboard profiles with on the fly DPI settings allow you to take your mouse anywhere
  • 3 zone RGB Lighting customizable via the UNLEASH RGB software
  • Ergonomic design with multipurpose MMO Pannel w/ 12 buttons, access multi-layer controls and more buttons according to your needs through the physical E-Shift function system. Powered by EVGA UNLEASH RGB software
Rank No. #2
Redragon M908 Impact RGB LED MMO Gaming Mouse with 12 Side Buttons, Optical Wired Ergonomic Gamer Mouse with Max 12,400DPI, High Precision, 20 Programmable Macro Shortcuts, Comfort Grip
  • Professional Gaming Mouse - Redragon M908 optical gaming mouse is designed with up to 12400 DPI, 5 adjustable DPI levels (500/1000/2000/3000/6200 DPI) meet your multiple needs, either for daily work or gaming. DPI can be adjusted freely by ±100 from 100 to 12400 via software. 1000 Hz polling rate, 30G acceleration and high-precision Pixart PAW3327 Sensor giving you a greater edge over your competition.
  • RGB Backlight & Programmable Buttons - 16.8 million RGB LED color options (LED Backlight can be disabled). 18 programmable buttons, 5 memory profiles each with a dedicated light color for quick identification. Comes with 8-piece weight tuning set (2.4g x8), easy to change the weight to suit your games.
  • Comfort & Precision At Your Hands - Redragon M908 gaming mouse is an essential computer accessory for die-hard gamers with its aggressive design for hands! You will be amazed by the unmatched comfort, lethal accuracy and killer precision of our durable, desktop and laptop pro gaming mouse!
  • High-end Design - Redragon M908 Mouse features 8 buttons and 12 MMO programmable side buttons. Durable smooth TEFLON feet pads for ultimate gaming control. 6ft braided-fiber cable with gold-plated USB connector ensures greater durability.
  • Die-hard Gamers Choice - Whether you are targeting, aiming, slashing or attacking, a professional gaming mouse is your basic weapon! The mouse will be your ideal partner. Compatible with Windows 2000/ME/XP/03/VISTA/7/8/10 system for programmable using and Mac OS for normal using.
SaleRank No. #3
Logitech G600 MMO Gaming Mouse, RGB Backlit, 20 Programmable Buttons, Black
  • 20 MMO tuned buttons: Includes unique 12 button thumb panel designed for quick, no look navigation; The low friction polytetrafluoroethylene feet eliminate friction on nearly any surface for smoother motions, precise cursor movements and improved accuracy
  • G shift ring finger button: Instantly double the number of actions you can perform with every button. PTFE Feet: 250-km range. Onboard memory: 1 profile
  • Built for comfort: Sculpted shape and tuned buttons reduce click fatigue during marathon multiplayer sessions; G8 cycle modes
  • Total personalization: Set it up your way with customizable thumb panel lighting colors, DPI levels or button assignments; Do not use a USB hub
  • Made for PC gaming: Compatible with Windows Vista, Windows 7 and Windows 8
SaleRank No. #4
Razer Naga X Wired MMO Gaming Mouse: 18K DPI Optical Sensor - 2nd-gen Optical Switch - Chroma RGB Lighting - 16 Programmable Buttons - 85g - Classic Black
  • Faster Than Traditional Mechanical Switches: New 2nd Gen Razer optical mouse switches uses light beam-based actuation, registering button presses at the speed of light
  • High-Precision 18,000 DPI 5G Optical Sensor: Offers on-the-fly sensitivity adjustment through dedicated DPI buttons (reprogrammable) for gaming
  • 16 Programmable Buttons: Allows for button remapping and assignment of complex macro functions through Razer Synapse
  • Immersive, Customizable Chroma RGB Lighting: Supports 16.8 million colors w, included preset profiles; syncs with gameplay and Razer Chroma-enabled peripherals and Philips Hue products
  • Drag-Free Cord for Wireless-Like Performance: Razer Speedflex cables eliminate the need for mouse bungees, drastically reducing weight and drag for absolute control
SaleRank No. #5
Logitech G502 SE Hero High Performance RGB Gaming Mouse with 11 Programmable Buttons
  • High performance hero 16k sensor: Logitech most accurate sensor yet with upto 16,000 dpi for the ultimate in gaming speed, accuracy and responsiveness across entire dpi range
  • 11 customizable buttons and onboard memory: Assign custom commands to the buttons and save Upto five ready to play profiles directly to the mouse
  • Adjustable weight system: Arrange upto five removable 3.6 gram weights inside the mouse for personalized weight and balance tuning. Requirements - Windows 7 or later. macOS 10.11 or later. Chrome OS. USB port
  • Programmable RGB lighting and lightsync technology: Customize lighting from nearly 16.8 million colors to match your team's colors, sport your own or sync colors with other Logitech G Gear
  • Mechanical switch button tensioning: Metal spring tensioning system and pivot hinges are built into left and right gaming mouse buttons for a crisp, clean click feel with rapid click feedback
Rank No. #6
UtechSmart Venus Gaming Mouse RGB Wired, 16400 DPI High Precision Laser Programmable MMO Computer Gaming Mice [IGN's Recommendation]
  • 『SENSITIVE DPI MMO MOUSE』Focus on MMO gamers: this professional MMO gaming mouse built-in up to 16400 DPI, 12000 FPS, 1000 Hz polling rate, 30G acceleration, 100-150in/s cursor speed, and a high precision Avago sensor. It has an adjustable sensitivity level (range from 200 - 16400) built right into the gaming mouse. You can easily adjust the mouse sensitivity using buttons on the mouse. Great micro switches provide crisp, firm clicks.
  • 『FULLY CUSTOMIZABLE MOUSE & RGB BACKLIT』Venus MMO wired gaming mouse with multiple programmable buttons (included 12 side buttons), 5 custom profiles each with 5 LED RGB colors backlit modes for quick identification of profiles and additional options for over 16 million LED RGB colors. The LED breathing light can be disabled according to your preference. Special Setting Switch Button on the bottom of the wired gaming mouse allows you to execute the switch profile command with maximum efficiency.
  • 『PROGRAMMABLE MOUSE BUTTONS』All the macro buttons allow you to customize the functions to your specific needs and can be easily mapped to any of the usual keyboard keys, combos. Venus MMO gaming mouse with side buttons can be mapped to what will best fit your style of play are placed within easy reach of your thumb. “Auto Fire button" is a convenient key for most games that can optimize your preferences. It makes gaming so much easier and even has the ability to increase your level of gameplay.
  • 『PRECISE CONTROL IN YOUR HAND』Venus MMO mouse is also an adjustable weighted mouse that comes pre-assembled with (2. 4g) x 8 weights inside. 12 buttons on the side are angled and can be positioned faster by touch alone. The Venus gaming mouse has a nice rest place on the left where your thumb can rest when not active. Comes with two durable smooth TEFLON feet pads for the bottom of the mouse to make the mouse slide better and bring the ultimate gaming experience for you.
  • 『COMFORTABLE SHAPE & TEXTURED GRIP』 Ergonomic Right-Handed design with the frosted painting surface avoids hand sweat and slippery. The shape and texture on the mouse are extremely comfortable in the hand and the size is suited for most. That can keep your grip firm during gameplay. 6ft braided-fiber cable with gold-plated USB connector ensures greater durability. 18-Month Manufacturer's Promise.
SaleRank No. #7
Redragon M801 Gaming Mouse LED RGB Backlit MMO 9 Programmable Buttons Mouse with Macro Recording Side Buttons Rapid Fire Button 16000 DPI for Windows PC Gamer (Wireless, Black)
  • PROFESSIONAL GRADE WIRED / WIRELESS GAMING MOUSE; featuring ultra-fast lag free wired or wireless connection. The rechargeable mouse features a battery life up to 35 hours (RGB LED on) up to 70 hours (RGB LED off) on a single charge. Pro Gaming features with 16000 user adjustable DPI and 40G acceleration. The High-Precision Sensor delivers Pinpoint Accuracy and extreme responsiveness during PC Gaming or Computer editing
  • RGB BACKLIT PROGRAMMABLE PC GAMING MOUSE; with 8 Lighting Effects, 10 Brightness Levels, Breathing Modes, (Backlight can be disabled), 9 user programmable buttons, 2 Side Buttons, Rapid Fire Button, 5 Memory Profiles with Macro Recording
  • ERGONOMIC GAMER MOUSE; Delivering an extremely comfortable and precise experience for Computer Games.
  • MMO GAMING MOUSE FEATURES; The Redragon M801P RGB Mouse features; Set Anti-Skid Scroll Wheel, Durable smooth TEFLON feet pads for ultimate gaming control. 9 programmable buttons. Comes with detachable 6 foot, 3mm strong high-speed braided fiber USB-C cable
  • PC GAMING MOUSE COMPATIBILITY: Windows 10, Windows 8, Windows 7, Windows Vista, or Windows XP, Limited Mac OS support Works well with all major Gaming Computers Brands and Gaming Laptops.
Rank No. #8
Logitech G604 LIGHTSPEED Gaming Mouse with 15 programmable controls, up to 240 hour battery life, dual wireless connectivity modes, hyper-fast scroll wheel - Black
  • 15 programmable controls: include 6 thumb buttons; fully programmable with G hub software
  • DUAL CONNECTIVITY: Toggle between convenient Bluetooth and ultra fast 1 mms LIGHTSPEED advanced wireless technology. Bluetooth report rate: 88 133 Hz (7.5 11.25 ms)
  • Hero 25K sensor through a software update from G HUB, this upgrade is free to all players: Our most advanced, with 1:1 tracking, 400-plus ips, and 100 - 25,600 max dpi sensitivity plus zero smoothing, filtering, or acceleration
  • DUAL MODE HYPERFAST SCROLL WHEEL: Durable metal scroll wheel switches between hyper fast and ratchetted scrolling; Programmable scrolling lets you apply key binds
  • 240 HOURS WITH 1 AA: efficient HERO 16K allows for 240 hours in LIGHTSPEED mode or up to 5; 5 months in Bluetooth mode
Rank No. #9
12 Programmable Buttons C12 Gaming Mouse, AFUNTA Laser Double-Speed Adjustment 8000DPI Mice Support 4 Level Switch
  • Durable smooth TEFLON feet pads and contoured body for ultimate gaming control. High-end features including: 12 buttons, pulsing light in 6 color modes, and 12 MMO programmable side buttons.
  • Support 4 level DPI: Support 1000-1500-2000-4000 4 levels DPI switch, you can choose the DPI level as you please, support double-speed adjustment,the highest mouse movement speed up to 8000DPI.
  • Quick thumb function: Original with 6 number keys on the left side, can be self programmed to any other functional keys to provide you a convenient thumb operate experience. Ergonomic design, internally and externally, to create the ultimate game concept.
  • Fire Key: triple click botton on the right,more convenient for you to get a triple click, help you to get a fast speed than other players in the game.Built-in 8 weights, can be adjusted according to your habit.
  • LED Light Mode Flash: 7- color cycle breathing effect, provide cool appreance. High-end 6ft braided-fiber cable with gold-plated USB connector for greatest durability and signal accuracy.
SaleRank No. #10
Redragon M901 Gaming Mouse RGB Backlit MMO 19 Macro Programmable Buttons with Weight Tuning Set, 12400 DPI for Windows PC Computer (Wired, Black)
  • Wired PC Gaming Mouse with up to 12400 DPI via software, 1000 Hz polling rate, 30G acceleration. The High-Precision Sensor delivers Pinpoint Accuracy while the Micro Switch ensure longevity, greater durability
  • RGB Backlit Macro Programmable Gaming Mouse 19 programmable buttons 5 Memory Profiles each with distinct LED color option for quick identification. Comes with 8-piece weight tuning set (2.4g x8) and 8 different lighting modes
  • Ergonomic Gamer Mouse; Ergonomic shape fits naturally in your hand, reduces stress with superior productivity and efficiency. Give an extremely gaming experience during sessions
  • PC GAMING MOUSE FEATURES; 7 Mouse Buttons PLUS 12 MMO programmable side buttons. Total 20 buttons. Fire button, Pulsing Breathing light color modes. Durable smooth TEFLON feet pads for ultimate gaming control
  • PC Gaming Mouse Compatibility: Windows 10, Windows 8, Windows 7, Windows Vista, or Windows XP, Limited Mac OS keyboard support. Comes with 6 foot high-speed braided fibre cable and a gold-plated corrosion free USB connector for a reliable connection

Last update on 2022-09-07 / Affiliate links / Images from Amazon Product Advertising API

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  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their gaming mouse programmable buttons.
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