The Best Hypoallergenic Matress Cover of 2022 – Reviewed and Top Rated
After hours researching and comparing all models on the market, we find out the Best Hypoallergenic Matress Cover of 2022. Check our ranking below.
2,293 Reviews Scanned
Rank No. #1
AllerEase Waterproof Mattress Protector, Maximum Allergy Mattress Protector, Twin Zippered Mattress Cover
- ALLERGEN BARRIER: Purely Clean Pro technology blocks 99.9% of unhealthy household allergens from passing through the fabric and collecting in your mattress.
- WATERPROOF: Soft, quiet top fabric is backed by a waterproof layer, protecting your mattress from unexpected spills & stains.
- FLEXFIT: Elastic corners ensure the perfect fit, tightly holding twin and full mattresses up to 14 inches deep, and Queen, King, and Cal King mattresses up to 17 inches.
- MACHINE WASH: Conveniently machine washable for easy care and a clean, healthy bedroom.
- LIFETIME WARRANTY: For peace of mind that you’ve made the clean, healthy choice for you and your family!
Rank No. #2
SafeRest Waterproof Queen Size Mattress Protector - Fitted with Stretchable Pockets - Machine Washable Cotton Mattress Cover for Bed
- KEEP YOUR MATTRESS DRY - Helps protect against fluids, urine, perspiration and anything else that might stain your mattress!
- QUIET & BREATHABLE - Quiet breathable Queen mattress protector that will allow a full night sleep while protecting your mattress
- PROTECT YOUR MATTRESS - Perfectly fitted Queen mattress protector that protects against unwanted creatures
- BEDDING ESSENTIALS - Airbnb Essentials for Hosts, Essential for first home and/or new apartment
- MACHINE WASHABLE - Machine washable on cold and tumble dry once cleaned
SaleRank No. #3
100% Waterproof Queen Mattress Protector Breathable Cooling 3D Air Fabric Mattress Cover Smooth Soft Hypoallergenic Noiseless Bed Cover Machine Washable Vinyl Free, 8-21'' Deep Pocket
- 100% WATERPROOF - Made with 30% THICKER waterproof layer than others in the market, BOSANE super waterproof mattress protector will protect your treasured mattress from every last drop and make it stay fresh and clean for decades!
- 100% HYPOALLERGENIC & SAFE MATTRESS COVER PROVED BY OEKO-TEX STANDARD 100 CERTIFICATE! - You can rest assured that you can sleep directly on our mattress protector queen which is made of 38% bamboo rayon, 62% polyester with NO chemical bleach and 0 harmful substances like vinyl and benzene. The bamboo fiber gives you ultra soft comfort and is great at sweat and odor wicking, the polyester meanwhile offers the flexibility and durability against the wear and tear to make it last for years.
- 100% QUIET & BREATHABLE - Featuring advanced 3D air mesh design and breathable membrane, BOSANE queen size mattress protector allows air to come out and flow through the thousands of holes on the surface to carry out the heat without a hinch. Fitting all kinds of mattress tightly from 8" to 21" height, our 18" stretchy pocket ensures this bed cover queen won't slide around and make noise when you toss and turn.
- 100% MACHINE WASH FRIENDLY, SUPPORT TUMBLE DRY - Need clean it regularly? Just toss it into the machine and wash it in the cold water. The US PATENTED compound adhesive enables our queen mattress cover to keep waterproof after over 500 machine wash cycles(about 10 Years) and support low-temp tumble dry below 122℉. Easy Clean, Easy Life!
- 100% HASSLE-FREE AFTER-SALE SERVICE - We always hold the belief that our queen waterproof mattress protector will save your life from avoidable problems and keep you from every little frustration. That also applies to our service. Each mattress protector from us is backed with the 10-year after sale servce and we promise the hassle-free replacement or refund without the need to RETURN if you are unsatisfied with the product!
SaleRank No. #4
Amazon Basics Hypoallergenic Quilted Mattress Topper Pad, Cover 18 Inches Deep, Full, White
- Mattress topper pad offers an added layer of comfort and helps protect the mattress
- Includes a Full 74.8 x 53.9 x 17.7-inch mattress topper
- Poly-cotton fabric for breathability; lightweight hypoallergenic fill that's ideal for allergy sufferers; quilted pockets prevent plush fill from shifting
- Knitted fabric sides with elastic for a secure fit on mattresses up to 18 inches deep
- Made in OEKO-TEX Standard 100 factory, an independent certification system that ensures textiles meet high safety and environmental standards
Rank No. #5
HOSPITOLOGY PRODUCTS Mattress Encasement - Zippered Bed Bug Dust Mite Proof Hypoallergenic - Sleep Defense System - Queen - Waterproof - Stretchable - Standard 12" Depth - 60" W x 80" L
- Zippered mattress cover stretches to fit any Queen (60” x 80”) standard mattress depth from 12" to 18"
- 100% Waterproof barrier on all six sides of mattress - Lab-tested
- Extra-soft polyester knit fabric is cool and comfortable - breathable waterproof membrane won't trap heat
- Can help improve sleep by reducing common substances that can reach the sleeper and disrupt respiratory function
- Machine washable - Tumble dry low - 5-Year Limited Manufacturer’s Warranty
Rank No. #6
100% Waterproof Full Mattress Protector, Hypoallergenic Viscose Made from Bamboo Mattress Cover, Breathable Cooling 3D Air Fabric Noiseless Bed Cover, Machine Washable Vinyl Free 8-16'' Deep Pocket
- 100% WATERPROOF & WALLET-SMART - Emircey Home waterproof mattress protector is made with the premium composite TPU material that effectively blocks liquids, dust, and stains, protecting your treasured mattress. Whether it's a child's bedwetting or a pet accident, our mattress cover has got you covered. Even after 500 washes, the upgraded TPU waterproof layer still performs well — keeping your mattress fresh and clean for years. One smart investment, long-term value you can count on!
- SAFE SLEEP & RESTFUL NIGHTS - Certified by OEKO-TEX Standard 100, our bed cover is made from 38% rayon derived from bamboo and 62% polyester, ensuring it' s hypoallergenic, odorless, and free from harmful chemicals such as bleach, vinyl, and benzene. So it is ideal for families with children, pets, or elderly. The bamboo viscose keeps your bedding comfort and dry by wicking away moisture and odors. Enjoy a hypoallergenic sleep surface for a cleaner, better night's rest - for you and your family.
- BREATHABLE & QUIET - This is the ideal mattress protector for hot sleepers. The 3D air mesh surface and breathable membrane not only are soft to the touch, but improve airflow for a cool and airy night's sleep. Also, our full mattress cover with premium fabric is wrinkle-free and has no plastic feel. It is completely silent - no crinkling noise! You'll sleep soundly all night no matter how you toss and turn.
- EASY USE & MACHINE WASHABLE - The 360° elastic band makes the mattress pad easy to put on. With deep elastic pockets, our full size mattress protector fits mattresses 8" to 16" thick. No matter how you move, the mattress cover stays put all night. The mattress protector is hassle-free to clean—just toss it in the washing machine with cold water and tumble dry on low heat (below 122°F). Note: do not iron, bleach, or dry clean. Effortless upkeep, fresh again!
- HASSLE-FREE AFTER-SALE SERVICE & 10-YEAR WARRANTY - Our premium full mattress protector waterproof are designed to ensure you have a cosy and content sleep experience every day. We are committed to providing top-notch service, offering a 10-year after-sales guarantee with every purchase. If you are not completely satisfied, we provide free replacements or refunds without the need for a return!
Rank No. #7
SureGuard Queen Size Mattress Protector - 100% Waterproof, Hypoallergenic - Premium Fitted Cotton Cover - Smooth
- 100% Waterproof - Top protection against perspiration, bed wetting, liquids and stains; 10-year quality guarantee (NOTE: For six-sided protection, buy a SureGuard Mattress Encasement).
- Keeps Your Mattress Clean & Fresh - Blocks dust, dirt and dander on the top side. Buy together with SureGuard Pillow Protectors.
- Soft & Noiseless - Smooth 100% cotton surface; Wicks away moisture; Retains the feel of your mattress - Free from Vinyl, PVC, Phthalates, fire retardants and other toxic chemicals
- Durable & Easy to Clean - Machine wash & dry - For frequent accidents, buy 2 or more - while one is washed, the other protects the mattress
- Queen (60 in x 80 in) - Fitted Sheet Style; Stretchable skirt fits any depth mattress. Independently lab tested and GREENGUARD Gold certified.
SaleRank No. #8
Queen Size Mattress Protector Bedbug Waterproof Zippered Cover Hypoallergenic Premium Quality Encasement White
- SIX SIDED ZIPPERED ENCASEMENT - Completely encases your mattress on all sides. Our premium zippered encasements are equipped with a Velcro zipper seal to ensure that nothing gets in! Say good-bye to troublesome pets that can ruin your mattress and bring discomfort to your life. Take precaution and sleep worry-free knowing that your mattress is shielded and protected. Be smart and protect your investment with a quality mattress encasement!
- WATERPROOF - Whether you have pets or kids, accidents and spills happen. This 100% waterproof mattress protector has a polyurethane inner lining that blocks liquids and moisture from getting in. Liquids easily seep through to deeper layers of your mattress and are almost impossible to remove. Simply wrap your mattress in our premium cover, zipper seal all the way around, and your mattress will remain waterproof, dry and protected!
- SOFT & NOISELESS - Stretchable, breathable fabric keeps liquids and contaminants out without compromising comfort. Designed to be soft and completely noiseless, you will not see or hear crinkles under your sheets. With our high quality mattress protectors, you are shielded from irritating contaminants that can sneak into the deep layers of your mattress! Seal out dust, pet hair for good!
- EASY INSTALLATION - Our mattress covers have a full zipper that wraps all the way around three sides of the mattress. No more struggling squeezing your mattress into difficult encasements, simply place your mattress in the sealed end and zip all the way around it for a perfect fit.
- DURABLE & LONG LASTING - Made of high quality polyester (surface) and polyurethane (inside lining). Featuring a 3” secondary polyester lining wrapping all around the zipper seam for additional durability and added support. This six-sided stretch fabric zippered mattress encasement is built to fit any Queen size mattress that is 12” to 16” deep. Machine washable for easy cleaning and lasting use.
Rank No. #9
Twin XL (6-8 in. Deep) SureGuard Mattress Encasement - 100% Waterproof, Bed Bug Proof, Hypoallergenic - Premium Zippered Six-Sided Cover
- 100% Waterproof - Six-sided premium mattress protector blocks perspiration, bed wetting, liquids and stains; 10-year quality guarantee (NOTE: For frequent accidents and easy clean-ups, place a fitted SureGuard Mattress Protector over the encasement).
- Bed Bug Proof - Super fine zipper with Invisi-Zip and SureSeal technology completely seals off the mattress from bed bugs - use with a SureGuard Box Spring Encasement
- Keeps Your Mattress Clean & Fresh - Blocks dust, dirt and dander on all sides.
- Soft & Noiseless - 100% cotton terry top; Wicks away moisture; Retains the feel of your mattress - Free from Vinyl, PVC, Phthalates, fire retardants and other toxic chemicals
- Twin XL (39 in x 80 in) - Fits 6 to 8 inches deep; Zippered Mattress Encasement - Machine wash and dry. Independently lab tested and GREENGUARD Gold certified. Buy 2 for a Split King
SaleRank No. #10
Waterproof Mattress Pad Protector Cotton Hypoallergenic Breathable Mattress Pad Cover, Deep Pocket
- 【Terry Cotton & Waterproof Layer】Our mattress pad is made from Terry Cotton with terry surface and waterproof TPU membrane layer to give you a delicate touch of nature & immense softness, and protect your mattress from fluid spills like sweat and urine.
- 【Breathable Layer & Immersive Sleeping】Inspired by the idea of ‘Naked-Sleep in the Bosom of Nature’ with absolute organic cotton blending surface and Airflow Technology to allow air to circulate in the bedroom. Provide you with an immersive and cozy slumber.
- 【Hypoallergenic】Our premium mattress pad offers you the protection against dust, fluids, urine and perspiration, giving you a cleaner and more comfortable sleeping environment.
- 【Easy to Clean & Easy to Fit】Our mattress pad can easily fit your bed with an elegant look. Machine wash and dry - buy 2 or more - while one is washed, the other protects the mattress. An elastic band is used on the side skirt to automatically fit mattresses with 18 - Inch height.
- 【Best Guard for Your Mattress】Work great for those with kids, toddlers or pets. With our waterproof mattress protector, you will have no more worries that your mattress gets fluids and stains, no more hassle of clean-up. You will have a wonderful sleeping experience with this product.
Last update on 2025-07-15 / Affiliate links / Images from Amazon Product Advertising API
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